C0 Adjust Pack Calibrations on the Atellica® Solution Job Aid Version 1.26 and Above

Atellica® Solution SIEMENS C0 Adjust Pack Calibrations Job Aid Healthineers Siemens Healthineers Assays C0 Adjust Pack Calibrations – the Principles that use C0 Adjust Calibrations: What is it: *Acet *Trig ➢ A calibration that only uses one low level calibrator Chol_2 UA ➢ An adjustment of an existing calibration - there must be a Lot calibration to adjust GluO UN_C Is not a calibration type that can stand on its own If there is no lot calibration for the assay, the pack calibration will be a full calibration requiring calibrators ETOH PAmy o The CH assay test definition specifies the type of pack calibration an assay requires. IP Only select CH assays, shown in the chart to the right, use C0 Adjust pack calibrations using the CH Diluent, requiring no calibrator to be loaded. *NOTE: On Atellica CH Analyzers, Acet uses C0 Adjust. However, on Atellica CI Analyzers, Acet For operator-defined assays that use C0 Adjust pack calibrations, either a zero-level calibrator or CH Diluent is uses a full pack calibration. o used as the calibrator The assay Trig uses C0 Adjust, but Trig_2 (a newer version) does not use C0 Adjust. The The C0 Adjust calibrations are a linear calibration adjustment and use two terms to calculate a SMN can be used to confirm which version you are running. result – C0 and C1 C0: CH Diluent is used to adjust the calibration coefficient for the intercept term C0 for Did you know that C0 adjust is also referred to o the C0 adjust calibrations as a common term called a “Blank?” Pack calibrations requiring a blank and not a full o **C1: The slope term C1, or the slope of the calibration curve, is a unit of absorbance/unit of analyte pack calibration use C0 Adjust. **NOTE: (C1) for C0 adjust calibrations is derived from the previous full, viable calibration that utilized calibrator material. Refer to Online Help for more information on how the calibration coefficients are used. 1 Template Effective Date: 10 Aug 2021 | HILS 2223 Effective Date: 30-OCT-2024 | QR700014483 Unrestricted I Published by Siemens Healthineers AG | © Siemens Healthineers AG, 2024 Atellica® Solution SIEMENS C0 Adjust Pack Calibrations Job Aid Healthineers Setup > Callbration Setup Automatic Calibration Orders Automatic calibration is designed to perform all calibrations needed for the day, at a time Calibration Ordering that will not interfere with regular patient processing. Ordering Mode * By System • When choosing the Calibration Time (labeled A in the image on the right), select an off- Automatic Order Calibrations peak time for your lab. Enabled Order QC with Callbration For assays with calibration intervals of greater than 48 hours: Perform QC with Calibration Enabled • The Calibration Time setting is used to determine when automatic calibration orders are created (labeled A in the image on the right) Callbration Time A Time • Each day at the Calibration Time, automatic calibration orders are created for any 01:00 AM calibrations that will expire through tomorrow’s Calibration Time For assays with calibration intervals of less than 48 hours: Calibration Due Configuration • The Calibration Due Warning setting is used to determine when automatic calibration B Calibration Due Warning (hours) * orders are created (labeled B in the image on the right) • When a calibration will expire within the Calibration Due Warning time, an automatic calibration order is created NOTE: The Calibration Due Warning setting is also used to trigger a warning (red Calibration Due tile) if there are • This includes C0 Adjust assays calibrations that require operation intervention (for example loading a material) within the configured hours. NOTE: Refer to the Calibration Scheduling on the Atellica® Solution Job Aid and Atellica® Solution Master List Job Aid on PEPconnect for more information. 2 Effective Date: 30-OCT-2024 | QR700014483 Unrestricted I Published by Siemens Healthineers AG | © Siemens Healthineers AG, 2024 Atellica® Solution SIEMENS C0 Adjust Pack Calibrations Job Aid Healthineers Automatic Calibration Orders - Examples Callbration > Calibration Due Timeframe Today and Tomorrow i Calibration Ordering Settings: Automatic Scheduled Time: 8:00 AM Calibration Warning: 1 hour Assay: Acet Pack Calibration Interval: 1 day It is currently 7am. If the current calibration will expire at 3pm this afternoon, when will the calibration order be created? Assay: Bnz Pack Calibration Interval: 20 days It is currently 7am. If the current calibration will expire at 3pm this afternoon, when will the calibration order be created? 3 Effective Date: 30-OCT-2024 | QR700014483 Unrestricted I Published by Siemens Healthineers AG | © Siemens Healthineers AG, 2024 Atellica® Solution SIEMENS C0 Adjust Pack Calibrations Job Aid Healthineers Automatic Calibration Orders - Examples (Answer Key) Calibration > Calibration Due Timeframe Today and Tomorrow i Calibration Ordering Settings: Automatic Scheduled Time: 8:00 AM Calibration Warning: 1 hour Assay: Acet Pack Calibration Interval: 1 day It is currently 7am. If the current calibration will expire at 3pm this afternoon, when will the calibration order be created? The calibration order will be created at 2pm. Since this assay has a calibration interval of less than 48 hours, the automatic calibration orders will be created based on the calibration warning time (in this case 1 hour because the expiration time). Assay: Bnz Pack Calibration Interval: 20 days It is currently 7am. If the current calibration will expire at 3pm this afternoon, when will the calibration order be created? The calibration order will be created at 8am. Since this assay has a calibration interval of greater than 48 hours, the automatic calibration orders will be created at the Scheduled Time (Calibration Time). 4 Effective Date: 30-OCT-2024 | QR700014483 Unrestricted I Published by Siemens Healthineers AG | © Siemens Healthineers AG, 2024 Atellica® Solution SIEMENS C0 Adjust Pack Calibrations Job Aid Healthineers Manual Calibration Ordering When troubleshooting an issue, you may want to be able to order a full pack calibration, even if a C0 adjust calibration is sufficient. • This can be done by manually creating the calibration order using the Calibration Orders screen. o The Type to Run column can be used to specify the type of calibration. ‹ Â Orders > Callbration Orders Select By Select Reagents O Assay Assay v Reagent Pack ID Inventory Cal Exp In Use Type to Run Lot Cal Exp ( Material Chol2 0 323456-11112:well 1 1 3 d2h Pack 32 d 2 h Select Analyzer * CH-01 Chol2 O 323456-11112:well 2 100 Lot -- 32 d 2 h Pack Chol2 423456-11112:well 1 100 10 d 8 h 10 d 8 h Select Assay(s) for Calibration CO Adjust Q Search Chol2 O 423456-11112:well 1 100 10 d 8 h Pack 10 d 8 h 5 Effective Date: 30-OCT-2024 | QR700014483 Unrestricted I Published by Siemens Healthineers AG | © Siemens Healthineers AG, 2024 SIEMENS Healthineers Please note this learning material is for training purposes only. For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Please note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Siemens Healthineers HQ I Siemens Healthineers AG Siemensstr. 3 91301 Forchheim Germany Phone: +49 9191 18-0 siemens-healthineers.com 6 Effective Date: 30-OCT-2024 | QR700014483 Unrestricted I Published by Siemens Healthineers AG | © Siemens Healthineers AG, 2024