TimeCurve

SIEMENS Healthineers TimeCurve Template Effective Date: 26 Mar 2025 | QR700020784 1 This training material is based on the medical device syngo.basic VB60J. Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 Disclaimer SIEMENS Healthineers syngo.via Q Scanner AI-Rad Companion V syngo.via Syngo Carbon View&GO Space Please keep in mind that the user interface may differ slightly from what is shown in this Job Aid. The actual usage of the tool may differ slightly on the different host systems, for example on syngo.via, Syngo Carbon Space, syngo.via View&GO, AI-Rad Companion or on the scanner. The tool functionality defined in this Job Aid is applicable to any of the Siemens Healthineers products in which you find this tool. Template Effective Date: 26 Mar 2025 | QR700020784 2 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve SIEMENS Healthineers Table of contents Introduction 4 Dynamic evaluation 7 Starting the dynamic evaluation 8 Preparing the data in the TC-Layout 10 Defining the region of interest 12 The dynamic curves 15 Axes settings 22 x-axis 23 y-axis 25 Result table 28 Saving results 31 Technical details 33 TC-Layout selection 34 Dynamic data selection 35 Image segments in TC-Layouts 36 Template Effective Date: 26 Mar 2025 | QR700020784 3 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Introduction Template Effective Date: 26 Mar 2025 | QR700020784 4 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve SIEMENS Healthineers Introduction (I) Carcinoma - Dynamic evaluation Abnormal perfusion – Dynamic evaluation Purpose TCT Aree D.94 cma Afin / Max 257.00 /1046 00 Mean/SD: 688.13/205 88 Ares: 0.94 cm2 Evaluate signal changes over time in dynamic Sun: 62804.00 94 Pres data sets. Post-surgery tumor – Dynamic evaluation BOLD paradigm – Dynamic evaluation TCI Dynartic Min / Max 726.00 /457 00 MganISO 350:13 :4261 Min/ Max 62.00 /954.00 Crex 1.73 cm2 MearYSD: 485 06 /211 48 MeNe: 440 00 /124.10 Sum 16907.00 re 1.73 cr2 Bur 28193.00 54 Pries 1 Fuels Motion artifacts Before starting a TimeCurve evaluation, 1 please check the images for motion artifacts, the TimeCurve functionality will not work properly and the results will not be reliable. Template Effective Date: 26 Mar 2025 | QR700020784 5 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve SIEMENS Healthineers Introduction (II) Viewing A A The TimeCurve tool offers: Dynamic TC1 TC2 › Viewing TC1 TC2 Min / Max:-198.00/770.00 Min / Max: 86.00/770.00 1 Min / Max: 3.00 /11 36.00 Min / Max: 710.00 /1196.00 - TimeCurve X Mean/SD: 716.94 /243.21 Mean/SD: 912.48 /1 28.88 Mean/SD: 371.59 /210.18 Mean/SD: 484.30 /170.48 Area: 1.20 cm2 Area: 0 23 cm2 Area: 1.20 cm2 Area: 0.23 cm2 Sum: 20987.00 Sum: 43476.00 Sum: 11139.00 O Sum: 83882.00 23 Pixels 117 Pixels 117 Pixels 1 • Three measurement tools to define the C-Circle TC-Pixel TC- TC- Lens Freehand Snapshot regions of interest (TC-ROIs). Basic Breast .................. Brain ......................... 2 • 5 Simultaneously evaluate of up to 10 TCS TOS 615 405.40 Breast 5x5 748.72 different regions of interest. Prostate Multi parametric 6 3 • Use different evaluation methods using absolute or normalized values. 4 • Represent signal evolution using .................................................. 3 normalized times, image numbers or trigger times. Mean (%) 1 300 250 2 5 • Five different TC-Layouts for MR dynamic 200 evaluations; one for other modalities. R 150 6 • Automatically propagate TC-ROIs within 100 dynamic data and from other MR data to 50 MR dynamic data. 0 50 100 150 200 250 300 350 ime Offset: 0 sec Normal Time (sec) 4 II Template Effective Date: 26 Mar 2025 | QR700020784 6 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Dynamic evaluation Template Effective Date: 26 Mar 2025 | QR700020784 7 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Starting the dynamic evaluation (I) Dynamics with patient motion TimeCurve layout Before starting a TimeCurve evaluation, you .-.-.-.- Dynamic TC1 A TC1 should check if there is patient motion in the Min / Max. 145.00 /530.00 Min / Max: 34.00 /748.00 Mean/SD: 248.67 /50.10 Mean/SD: 434 78 /146:97 dynamic data. Area: 1:02 cm2 Area: 1.02 cm2 Sum: 24867.00 Sum: 43478.00 100 Pixels 100 Pixels TCA TO4 Min / Max .110.00 /748.00 Check for changes in the anatomical position of Min / Max: 64.00/1010.00 Mean/SD 377 54 /207 09 Mean/SD: 280 46 /178 45 1 Area: 4.57 ern2 Area: 4.57 cm2 the scanned structures throughout the different Automatic Windowing Sunt: 166878.00 Sum 123962.00 Motion Correction (Elastic) Correction Tools R 442 Pixels R 442 Pixels dynamic acquisitions. 2D Distortion Correction ImageFilter Smooth Reverse 2D Distortion Correction Analysis Tools 3D Distortion Correction MR Presets If needed: MR Color LUT Reset Windowing -G Subtractions of the dynamics after Dynamics after motion correction motion correction 1 • Use the Motion Correction tool to create a Dynamics after motion correction 3 A new dynamic series. Mean (%) 200 2 • Utilize the Subtraction tool to create the 175 subtractions with the newly motion- 150 corrected dynamic series. 125 R 100 Automatic Windowing 75 3 Use these motion-corrected series auto • Correction Tools 50 2 ImageFilter Smooth 25 (dynamics and its subtractions) during the Subtraction - Analysis Tools + x - dynamic evaluation in TimeCurve. 50 100 150 200 250 Addition 300 350 + MR Presets Subtractions of the dynamics after Time Offset: 0 sec Normal Time (sec) Multiplication X MR Color LUT motion correction Division Reset Windowing Template Effective Date: 26 Mar 2025 | QR700020784 8 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Starting the dynamic evaluation (II) A A To start the TimeCurve tool: 1 Tool Gallery X 1 • Click the TimeCurve icon that you find in R R Q Search the Favorite Tools panel or in the Tool .................. . . . . . . . . . . . . . . . . ........ 1 Postprocessing Gallery. TimeCurve SPECTS Brain Hyperde. Viewing X A A Dynamic 2 • The application: › Viewing TimeCurve X • Switches to the TimeCurve panel. O TC -Circle TC-Pixel TC TC The corresponding TimeCurve Lens Freehand Snapshot • R 2 layout is applied. R Basic Breast • The TC-Circle tool is automatically activated. A TimeCurve layout The initial layout that opens with TimeCurve varies by modality and R TimeCurve Graph Segment anatomy. For MR images, change and H. select layouts for brain, breast, prostate, or multi-parametric imaging. Template Effective Date: 26 Mar 2025 | QR700020784 9 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Preparing the data in the TC-Layout (I) Dynamic data within the same series block = > Results MoCoHiQ_dynamics_Moco Perform the dynamic evaluation of data classified If all the dynamics are within the same series & Results MoCoHiQ_dynamics_Moco under the same series block: block in the Series panel, you can drag and 1002 : Phase_01 H. drop them to the Dynamic image segment. 1003 : Phase_02 1 • Check the TimeCurve layout. 1000 Phase_03 If evaluating MR data, ensure the 1004 : Phase_04 automatically selected layout meets your Viewing C * X A A Series needs. Otherwise, select another layout Dynamic › Viewing TimeCurve X 2 3 from the available ones. 7 Series Name TC-Circle TC TC Lens Freehand Snapshot 2 • Check the Dynamic image segment. R R 1/17/2022 2:08 PM Basic Breast 1 MR, Carcinoma_Dixon_Diff_CE_B17ch Ensure the dynamic data you want to Results Sub_sub_Moco Brain Results MoCoHiQ_dynam Moco evaluate are loaded in the Dynamic image Breast > t1_f3d nonfs_tra_p2 +3Messung _FA20º_SUB segment. Otherwise, drag and drop them Prostate > t1 f13d nonfs_tr /2_1+3Messung_FA20º 15 t1_f13d_no_tra_p2_1+3Messung_FA20º_SUB_MIP. from the Series panel to the Dynamic Multi parametric 14 > t1 9/@_nonfs_tra_p2_1+3Messung_FA20º_SUB_MIP ... A image segment. 10 diff_stir_b50_800_tra_p2_ORIG 9 diff_stir_b50_800_tra_p2_CALC_BVAL 18 diff_stir_b50_800_tra_p2_ADC 7 > diff_stir_b50_800_tra_p2 3 • If using an MR dedicated layout, ensure t2_tse_dixon_tra_p2_320 TE 119 the data in the other image segments are R TimeCurve Graph Segment 2 t2_tse_tra_p2 TE 170 FA 175 Baseres320 1 localizer correct for reliable propagation of the TC- ROIs. Otherwise, drag and drop them. 3 II Template Effective Date: 26 Mar 2025 | QR700020784 10 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Preparing the data in the TC-Layout (II) Dynamic data are not within one series block 16 t1_vibe_fs_tra_p4_bh_delay Perform the dynamic evaluation of data that are If the dynamic data are not within the same series block, you 15 t1_vibe_fs_tra_p4_bh_venos not classified within the same series block: need to Create Dynamic 4D after starting the TimeCurve tool. 14 t1_vibe_fs_tra_p4_bh_arteriel H. .-.-.. 11 t1_vibe_fs_tra_p4_bh_pre 1 • Check the TimeCurve layout. TimeCurve X Series If evaluating MR data, ensure the Dynamic O TC-Circle TC-Pixel 2 automatically selected layout meets your Lens Freehand Snapshot Series Name needs. Otherwise, select another layout Basic Multi 1 Please drag data from Series Navigat Please drag data from Series Navigator. 7124/2018 paramet .. MR, Tumor_CE_BLADE_BO18ch_SP32ch from the available ones. Insert Before Brain 16 t1_vibe_fs_tra_p4_bh_delay Create Dynamic 4D 15 t1_vibe_fs_tra_p4_bh_venös Breast Create 2D Stack 14 t1_vibe_fs_tra_p4_bh_arteriel 11 Prostate t1_vibe_fs_tra_p4_bh_pre 2 • Create Dynamic 4D. A ynamic A Series Multi parametric In the Series panel, select all the series you want to use as dynamic data. Drag and ~ B Series Name R R 7124/2018 drop them to the Dynamic image segment MR, Tumor_CE_BLADE_BO18ch_SP32ch Please drag data from Series Ne 16 t1_vibe fs tra p4_bh delay using the right mouse button. Select 15 t1_vibe_fs_tra_p4_bh_venos 14 11 vibe fs tra_ p4 bh arteriel 3 Create Dynamic 4D. 11 t1_vibe_fs_tra_p4_bh_pre 8 t2_blade_fs_tra_p3_trig? ? 320 7 t2 blade_tra_p3 3 • If you are using an MR dedicated layout, ensure the data in the other image segments are the correct ones for a R Time Curve Graph Segment reliable propagation of the TC-ROIs. 3 Otherwise, drag and drop them. Template Effective Date: 26 Mar 2025 | QR700020784 11 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Defining the region of interest (I) 1 2 3 Use three measurement tools to define the regions of interest (ROI) for evaluation. TimeCurve X TimeCurve X TimeCurve X O O O + 1 • TC-Circle TC-Circle TC-Pixel TC- TC- TC-Circle TC-Pixel TC- TC- TC-Circle TC-Pixel TC TC- Lens Freehand Snapshot Lens Freehand| Snapshot Lens Freehand Snapshot Draw a circular TC-ROI or an ellipsoid TC- ROI by pressing the Shift key. Basic Breast Basic Breast Basic Breast 2 • TC-Freehand TC Pixel Lens Properties ? X Draw a freehand TC-ROI. Dynamic A Dynami TC1 Min / Max: 111.00 /1028.00 TC1 TimeCurve Mean/SD: 640.90 /214.94 Min / Max: 22.00 /1028.00 Area: 0.44 cm2 Mean/SD: 608.04 /206.86 Size of Pixel Lens Sum: 26277.00 41 Pixels Sum: 78437.00 129 Pixels O 1x1 pixel 3 • TC-Pixel Lens and Pixel Lens Properties TC-Circle TC- R Lans hand 3x3 pixel 5x5 pixel Set a TC-ROI with a defined number of Pixel Lens Properties pixels (1x1 pixel, 3x3 pixels, 5x5 pixels). () Basic Breast OK Cancel TC-Circle and TC-Freehand values • Min/Max pixel statistics TC1 Dynamic Dynamic Min / Max: 22.00 /1028.00 Mean/SD: 598.79 /202.62 Dynamic Area: 1.00 cm2 • Mean/SDev pixel statistics H. 1028.00 Sum: 58681.00 Dynamic 98 Pixels • Area value 1 2.44 + Shift • Sum pixel statistics • Number of pixels in the ROI Template Effective Date: 26 Mar 2025 | QR700020784 12 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Defining the region of interest (II) Dynamic A The TC-Circle measurement tool is activated after TC1 TC1 Min / Max: 22.00 /1028.00 Min / Max: -38.00 /846.00 Mean/SD: 600.00 /194.81 Mean/SD: 519.25 /169.82 starting TimeCurve. Select another measurement Area: 1.84 cm2 Area: 1.84 cm2 Sum: 106200.00 Sum: 91907.00 177 Pixels 177 Pixels tool if needed. TC2 TC2 Min / Max: 22.00/1028.00 Min / Max: -110.00 /846.00 Mean/SD: 583.33 /178.26 Mean/SD: 358.55/226.06 Area: 4.31 cm2 Area: 4.31 cm2 Sum: 242080.00 Sum: 148797.00 With the left mouse button, you can define the 415 Pixels 415 Pixels TC3 TC3 TC-ROI in the Dynamic image segment. 5x5 399.52 .............. 5x5 281.20 TC4 TC4 Min / Max: 278.00 /920.00 Min / Max: 456.00 /846.00 Mean/SD: 690.52/176.07 Mean/SD: 660.52 /98.04 Identify the region of interest in other data types Area: 0.27 cm2 Area: 0.27 cm2 Sum: 17263.00 Sum: 16513:00 25 Pixels 25 Pixels (diffusion, maps, subtractions…). Mean (%) 300 Propagation of the TC-ROI 250 Draw a TC-ROI in an image segment 200 different from the Dynamic image H. R 150 segment. The application propagates 100 that TC-ROI to the data in the Dynamic So image segment and calculates its 0 50 100 150 200 250 300 350 dynamic curve. Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 13 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers Defining the region of interest (III) Dynamic TC1 TC1 Dynami Area 3 65 cm2 You can define the TC-ROI in another image Min / Max: 22.00 /1028.00 Min / Max: -38.00 /846.00 Mean/SD: 600.00 /194.81 Mean/SD: 519.25 /169.82 Area: 1.84 cm2 Area: 1.84 cm2 segment if its data and the data in the Dynamic Sum: 106200.00 Sum: 91907.00 177 Pixels 177 Pixels TG2 Min / Max 22:00 /1028.00 Min / Max-110.00 /846 00 image segment have: Mean/SD: 583.33/178.26 Mean/SD 358:55/228/06 Area: 4:31 cm2 Area 4 98 cm2 Sum 242080.00 Sum: 148797/00 415 Pixels 405 Phels • The same Frame of Reference. 5x5 281.20 TO Min / Max 456 304246 0 Min / Max 270,00 /920.00 Mean/so Bel 52/98 04 The same type of Distortion Correction. Mearv6D: 690 521/176.07 • Area: 0.27 cm2 Sum4177263100 Subtraction Subtraction Display Type 2D Display Type 2D • An interaction in plane within half slice TOO thickness. Min / Max: 26.00 /74.00 Mean/SD: 47.18 /11 28 Mean (%) Area 3.65 cm2 Sum: 6841:00 Mean (%) 145 Pixels 300 • A selected Display Type 2D. 250 200 150 150 The TC-ROI you define is automatically 100 100 propagated to the data in the Dynamic image Diffusion segment. 50 100 200 250 350 50 100 150 200 250 300 Display Type MIP Time Offset: 0.sec Normal Time (sec) Display Type 2D Time Offset: 0 sec Normal Time (sec) Mouse pointer when propagation is 1 possible The mouse pointer indicates in which image segments you can define a TC-ROI. Template Effective Date: 26 Mar 2025 | QR700020784 14 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (I) Dynamic TC TC1 Min / Max: 515.00 /1129.00 Min / Max: 192.00 /812.00 In the Result segment, check the signal intensity Mean/SD: 875.35 /145.10 Mean/SD: 491.35 /151.65 Area: 0.20 cm2 Area: 0.20 cm2 Sum: 17507.00 Sum: 9827.00 changes of the pixels in each TC-ROI. 20 Pixels 20 Pixels TC2 1 TC2 Min / Max: 311.00 /1129.00 Mean/SD: 749.65 /189.70 Min / Max: -75.00 /812.00 Area: 0.82 cm2 Mean/SD: 409.77 /188.63 Sum: 58473.00 Area: 0.82 cm2 TC1 78 Pixels ............ Sum 31962.00 78 Pixels 15.00 /1129.00 Min / Max: 192.00 /812.00 1 • Each TC-ROI is displayed in a different R 75.35 /145.10 Mean/SD: 491.35/151.65 TC3 TC3 cm2 Area: 0.20 cm2 color. In the Result segment, the Min / Max: 278.00 /1129.00 Mean/SD: 708.64 /154.81 Min / Max: -170.00/812.00 00 Sum: 9827.00 20 Pixels Area: 6.15 cm2 Mean/SD: 161.96/192.50 corresponding curve is displayed in the Sum: 426604.00 Area: 6.15 cm2 602 Pixels Sum: 97497.00 TC2 602 Pixels 11.00 /1129.00 49.65 /189.70 Min / Max: -75.00/812.00 Mean/SD: 409.77 /188.63 m2 Area: 0.82 cm2 same color. 00 ............ Sum: 31962.00 78 Pixels 78.00 /1129.00 TC3 Min / Max: - 1 00 /812.0 08.64 /154.81 Mean/SD: 161.96/192.50 cm2 Area: 6.15 cm2 • You can simultaneously evaluate up to 10 Sum: 97497.00 2 04.00 602 Pixels TC-ROIs. Mean (%) 3 TC11 300 Min / Max: -86.00 /211.00 Mean/SD: 43.33 /52.14 Area: 2.24 cm2 250 Sum: 9445.00 218 Pixels 3 The TC-ROIs defined after the 10th are • 200 displayed in white, and the corresponding R 50 Mean (%) 2 curve is not calculated. 100 300 250 200 50 100 150 200 250 300 350 O Time Offset: 0 sec Normal Time (sec) 150 100 So 100 150 200 250 300 350 Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 15 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (II) A A TC1 Dynamic TC1 If necessary, scroll through the phases, Min / Max: 428.00 /1033.00 Min / Max: 440.00 /832.00 1 • Mean/SD: 715.85 /149.83 Mean/SD: 654.90 /111.66 Area: 0.20 cm2 Area: 0.20 cm2 and adjust the size and position of the 1 Sum: 14317.00 1 Sum: 13098.00 20 Pixels 20 Pixels TC-ROIs. TC2 TC2 Min / Max: 196.00 /1033:00 Min / Max: 265.00/832.00 Mean/SD: 649.06 /184.22 Area: 0.82 cm2 Mean/SD: 539.68 /145.62 Sum: 50627.00 .............. Area: 0.82 cm2 Sum: 42095.00 78 Pixels ......... 78 Pixels R TC3 R ..................... TC3 Min / Max: 164.00 /1034.00 Mean/SD: 627.73 /175.63 Min / Max: -145.00/832.00 Area: 6.15 cm2 Mean/SD: 278.08 /235.82 Sum: 377891.00 Area: 6.15 cm2 602 Pixels Sum: 167403.00 602 Pixels TC3 Normal Time: 135.32 sec Mean: 627.73 Ratio: 34.77 % Mean (%) 300 250 200 R 150 Pixel Lens Properties 100 If you change the size of the pixel lens, 50 the already defined TC-ROIs are not .................................................................................................... H. 0 50 100 150 250 300 350 updated. 200 Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 16 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (III) A TC1 TC1 Dynamic A Min / Max: 428.00 /1033.00 Min / Max: 440.00 /832.00 1 • If necessary, scroll through the phases, Mean/SD: 715.85 /149.83 Mean/SD: 654.90/111.66 Area: 0.20 cm2 Area: 0.20 cm2 and adjust the size and position of the 1 Sum: 14317.00 20 Pixels 1 Sum: 13098.00 20 Pixels TC-ROIs. TC2 TC2 Min / Max: 196.00 /1033.00 Mean/SD: 649.06 /184.22 Min / Max: 265.00 /832.00 Area: 0.82 cm2 Mean/SD: 539.68 /145.62 Sum: 50627.00 Area: 0.82 cm2 Sum: 42095.00 78 Pixels 2 • When you modify a TC-ROI, the 78 Pixels R TC3 R TC3 corresponding curve is accordingly Min / Max: 196.00 /1033.00 Mean/SD: 568.02 /173.19 Min / Max: 83.00 /832.00 Mean/SD: 497.30/153.56 updated. Area: 1.79 cm2 Sum: 96563.00 Area: 1.79 cm2 170 Pixels Sum: 84541.00 170 Pixels TC3 Normal Time: 135.32 sec Mean: 568.02 Ratio: 116.05 % Mean (%) 300 250 2 200 R 150 Pixel Lens Properties 100 If you change the size of the pixel lens, 50 the already defined TC-ROIs are not H. .................................................................................................................................... 0 50 100 150 200 250 updated. 300 350 Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 17 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (IV) A Dynamic TC1 A TC1 1 • You can navigate through the different Min / Max: 428.00 /1033.00 Min / Max: 440.00 /832.00 Mean/SD: 715.85 /149.83 Mean/SD: 654.90/111.66 Area: 0.20 cm2 Area: 0.20 cm2 phases of the data by clicking on the time Sum: 14317.00 Sum: 13098.00 20 Pixels 20 Pixels points of the curves. TC2 1 TC2 Min / Max: 196.00 /1033.00 Mean/SD: 649.06 /184.22 Min / Max: 265.00/832.00 Area: 0.82 cm2 Mean/SD: 539.68/145.62 Sum: 50627.00 Area: 0.82 cm2 78 Pixels Sum: 42095.00 78 Pixels ......... R TC3 R Min / Max: 196.00 /1033.00 TC3 Mean/SD: 568.02 /173.19 Min / Max: 83.00 /832.00 Area: 1.79 cm2 Mean/SD: 497.30/153.56 Sum: 96563.00 Area: 1.79 cm2 170 Pixels Sum: 84541.00 170 Pixels A TC3 Normal Time: 135.32 sec Mean: 568.02 Ratio: 116.05 % Mean (%) 1 300 250 200 R 150 100 50 1 0 50 100 150 200 250 300 350 Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 18 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (V) A TC1 Dynamic TC1 A You can navigate through the different Min / Max: 515.00 /1129.00 Min / Max: 192.00 /812.00 1 • Mean/SD: 875.35 /145.10 Mean/SD: 491.35 /151.65 Area: 0.20 cm2 Area: 0.20 cm2 phases of the data by clicking on the time 2 Sum: 17507.00 2 Sum: 9827.00 20 Pixels 20 Pixels points of the curves. TC2 TC2 Min / Max: 311.00 /1129.00 Mean/SD: 749.65 /189.70 Min / Max: -75.00 /812.00 Mean/SD: 409.77 /188.63 Area: 0.82 cm2 ............ Sum: 58473.00 Area: 0.82 cm2 Sum: 31962.00 The corresponding image segments are 78 Pixels • ............. 78 Pixels 2 ...... ............... R TC3 R TC3 updated with the selected time point Min / Max: 311.00 /1129.00 Mean/SD: 706.65 /170.15 Min / Max: -90.00/812.00 Mean/SD: 305.11 /189.17 (phase). Area: 1.79 cm2 Area: 1.79 cm2 Sum: 120130.00 170 Pixels Sum: 51868.00 170 Pixels A TC3 Normal Time: 230.65 sec Mean: 706.65 Ratio: 168.78 % Mean (%) 300 250 200 R 150 100 50 1 50 100 150 200 250 300 350 ime Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 19 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (VI) A Dynamic TC1 A TC1 • You can navigate through the slice Min / Max: 515.00 /1129.00 Min / Max: 192.00 /812.00 1 Mean/SD: 875.35 /145.10 Mean/SD: 491.35 /151.65 Area: 0.20 cm2 Area: 0.20 cm2 positions where you draw the TC-ROIs by Sum: 17507.00 Sum: 9827.00 20 Pixels 20 Pixels clicking on the different curves. TC2 TC2 Min / Max: 311.00 /1129.00 Mean/SD: 749.65 /189.70 Min / Max: -75.00 /812.00 .............. Mean/SD: 409.77 /188.63 Area: 0.82 cm2 Area: 0.82 cm2 Sum: 58473.00 78 Pixels Sum: 31962.00 78 Pixels R .................... TC3 R ................................................. Min / Max: 311.00 /1129.00 TC3 Mean/SD: 706.65 /170.15 Min / Max: -90.00/812.00 Area: 1.79 cm2 Mean/SD: 305.11/189.17 Sum: 120130.00 Area: 1.79 cm2 170 Pixels Sum: 51868.00 170 Pixels A TC3 Normal Time: 230.65 sec Mean: 706.65 Ratio: 168.78 % Mean (%) 300 250 200 R 150 100 50 1 0 50 100 1 50 200 250 300 350 O Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 20 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Dynamic evaluation SIEMENS Healthineers The dynamic curves (VII) A Dynamic TC8 A TC8 1 • You can navigate through the slice Min / Max: 710.00 /1083.00 Mean/SD: 914.25 /116.90 Min / Max: 86.00 /690.00 Area: 0.22 cm2 Mean/SD: 468.20/166.07 Area: 0.22 cm2 positions where you draw the TC-ROIs by 2 Sum: 18285.00 20 Pixels 2 Sum: 9364.00 20 Pixels clicking on the different curves. TC9 Min / Max: 3.00 /1136.00 TC9 Mean/SD: 718.56 /233.14 Min / Max: -198.00 /770.00 Area: 1.40 cm2 Mean/SD: 349.27 /208.31 Area: 1.40 cm2 2 • The corresponding image segments are Sum: 97005.00 135 Pixels ........... Sum: 47152.00 R R 135 Pixels updated with the slice position where the related TC-ROI is located. TC8 Normal Time: 230.65 sec Mean: 914.25 Ratio: 287.89 % Mean (%) 300 250 1 200 R 150 100 50 0 50 100 50 200 250 300 350 .......................................................................................................... Time Offset: 0 sec Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 21 Job Aid Effective Date: 15 May 2025 | QR700023281 Study ID: 7aaaa0309 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Axes settings Template Effective Date: 26 Mar 2025 | QR700020784 22 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Axes settings SIEMENS Healthineers x-axis (I) There are three different sorting options TC1 Normal Time: 0.2 sec Ratio: -98.79 % Mean (%) available: -10 -20 1 • Normal Time -30 Evaluate images sequentially based on acquisition time. The unit is seconds (sec). 50 -60 isec Mean: 1 Ratio: -98.79 % -70 2 • Trigger Time -80 Evaluate images sequentially based on -90 -100 trigger time. The unit is milliseconds 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 Time Offset: 0 sec Normal Time (sec) 1 (msec). 60 Mean: 1 Ratio: -98.79 % -70 3 • Image Number -80 Evaluate images sequentially based on -90 -100 image numbers. O 100 200 300 400 500 600 700 800 900 Trigger Time (msec) 2 To change the sorting, click on the interactive 70 label of the x-axis. -80 .90 -100 5 10 15 20 25 Image No. 3 Template Effective Date: 26 Mar 2025 | QR700020784 23 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Axes settings SIEMENS Healthineers x-axis (II) Scan and contrast administration simultaneously started Scan started 8 sec after When evaluating a contrast-enhanced (CE) MR contrast administration dynamics, the resulting signal curve gives Scan started 8 sec before patient-specific and region-specific information TC4 Normal Time: 25.55 sec ean: 68.05 Ratio: 3302.33 % Mean (%) contrast administration 3500 about the transit time of the contrast agent. TC4 Normal Time: 33.55 sec Mean: 68.05 Ratio: 3302.33 % 3000 Mean (%) 3500 2500 3000 TC Normal Time: 17.55 sec Mean: 68.05 Ratio: 3302.33 % To establish a common starting point for the Mean (%) 2000 3500 2500 beginning of the subsequent CE-MR 1500 3000 2000 measurement and the contrast agent injection, 1000 1500 2500 you can define a timing offset. 500 2000 1000 1500 500 500 The Time Offset option is available only 20 1000 1 • 10 2 30 50 Time Offset: 0 sec 1 Normal Time (sec) 500 when the sorting is set to Normal Time. -500 10 20 30 40 50 Time Offset: 8 sec 0 --------- ! Normal Time (sec) -500 Time Offset 2 Click the interactive image text Time -10 0 10 20 40 50 • Min/ Max: 20 00738.00 Time Offset: -8 sec Normal Time (sec) Mean/SD: 00 02 M 10 Offset. Ares 1 49 0ml 44 Pixels TC1 3 Time Offset Min / Max. 16.00/24:00 Time Relative to Start of Scan ? X Mean/SO: 19 78 /2: 14 Area. 1.52 cm2 Sum 811.00 Min / Max: 61.00 /75:00 41 Pixels MearySD: 6805 /3 05 RHA Area: 1 53 cm3 Time Offset 8.0 + sec 3 • Enter the necessary timing offset (in Sum: 2820:00 -10 sec = 10 seconds after start of scan Time Relative to Start of Scan 3 seconds) to get the Normal Time values TC3 +15 sec = 15 seconds prior start of scan Min / Max 58 00 /89.00 Mean/SD 62 93 /277 Time Offset -8.0 ¢ sec Area 1.51 cm2 relative to the start of the scan. Sum 2769.00 44 Pixels -10 sec = 10 seconds after start of scan OK Cancel +15 sec = 15 seconds prior start of scan OK Cancel Template Effective Date: 26 Mar 2025 | QR700020784 24 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Axes settings SIEMENS Healthineers y-axis (I) TC1 A The y-axis can either display mean absolute Min / Max: 279.00 /458.00 Dynamic Mean Mean/SD: 378.00 /75.27 values or mean normalized values. Area: 7.50 mm2 Sum: 3024.00 1 For each ROI “TCi”: 8 Pixels 𝑦𝑇𝐶𝑖(𝑥) = 𝑀𝑒𝑎𝑛𝑇𝐶𝑖(𝑥) To change the mode, click on the interactive text displayed on top of the y-axis. R 1 2 TC2 Normal Time: 230.65 sec Mean: 723.29 TC2 Min / Maxe 2 Mean i Mean values measure in respective units Mean/SD. 723.29 800 Mean Area: 1.96 youuwe Sum: 138871.00 192 Pixels 2 700 It provides the mean absolute value of all pixels 600 included in the region of interest (ROI). The 500 following values are provided: 400 1 • Normal Time/Trigger Time/Image No.: 300 x-axis value of the selected frame. 200 100 2 • Mean: 0 Mean value of all pixels in the selected ................................................................. 50 100 150 200 250 300 350 ROI. O Time Offset: 0 sec 1 Normal Time (sec) Template Effective Date: 26 Mar 2025 | QR700020784 25 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Axes settings SIEMENS Healthineers y-axis (II) TC1 A Mean (%) - Default setting Min / Max: 279.00 /458.00 Dynamic Mean (%) Mean/SD: 378.00 /75.27 Area: 7.50 mm2 For each ROI “TCi”: Sum: 3024.00 It calculates the mean normalized value, of all 8 Pixels 1 𝑦𝑇𝐶𝑖(𝑥) = 100 ∙ 𝑀𝑒𝑎𝑛𝑇𝐶𝑖 𝑥 − 𝑀𝑒𝑎𝑛𝑇𝐶𝑖(0) pixels within the ROI. This is done by comparing 𝑀𝑒𝑎𝑛𝑇𝐶𝑖(0) them to the mean value of the same ROI in the initial phase. In this case, the starting point of R -.-.-.-.-.- .................................................................................................................................................................. each curve is set to 0%, and the following values 1 2 3 are provided: TC2 Min / Max 2 TC2 Normal Time: 230.65 sec Mean: 723.29 Ratio: 178.09 % Mean/SD. 723.29 Area: 1.96 wwwg Mean (%) i Compare each ROI to its first phase(0%) Sum: 138871.00 1 • Normal Time/Trigger Time/Image No.: 182 Pixels 200 3 x-axis value of the selected frame. 175 150 2 • Initial phase Mean: 125 Mean value of all pixels in the selected ROI. Dynamic 100 TC1 Min / Max: 274.00 /334.00 Mean/SD: 295.25 /20.39 75 Area: 7.81 mm2 3 • Ratio (Mean (%)): Mean normalized value Sum: 2362.00 8 Pixels 50 of all pixels in the selected ROI. 25 0 Equivalent in the dedicated MR Workflows 0 50 100 150 200 250 300 350 TC2 Time Offset: 0 sec 1 Normal Time (sec) Please note: In the MeanCurve, this is Min / Max Reference equivalent to Relative to Reference Index. H. Mean/SD 280.09 Area: 1.90 wwww Sum: 49938.00 192 Pixels Template Effective Date: 26 Mar 2025 | QR700020784 26 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Axes settings SIEMENS Healthineers y-axis (III) TC1 A .00 458 namic Ratio (%) Ratio (%) Min / Max 2700 Mean/SD 378.00 Reference Area: 7.50- For each ROI “TCi”: It calculates the mean normalized value, of all Sum: 3024.00 8 Pixels 𝑀𝑒𝑎𝑛𝑇𝐶𝑖 𝑥 () pixels within the ROI. This is done by comparing 𝑦𝑇𝐶𝑖(𝑥) = 100 ∙ H. 𝑀𝑒𝑎𝑛𝑇𝐶1(𝑥) them to the mean value of the initial ROI in the same phase. The curve corresponding to the first R drawn ROI is set to 100%, and the following values 1 2 3 are provided: TC2 Min / Maxer 2 TC2 Normal Time: 230.65 sec Mean: 723.29 Ratio: 191.35 % Mean/SD: 723.29 Area: 1.96 terwwe Ratio (%) 1 Compare each phase to the value of first TC(100%) 1 • Normal Time/Trigger Time/Image No.: Sum: 138871.00 192 Pixels 250 x-axis value of the selected frame. 225 3 200 175 2 • Mean: 150 Mean value of all pixels in the selected ROI. 125 100 3 • Ratio (Ratio (%)): Mean normalized value of 75 all pixels in the selected ROI. 50 25 Equivalent in the dedicated MR Workflows O 0 50 100 150 200 250 300 350 1 Please note: In the MeanCurve, this is Time Offset: 0 sec 1 Normal Time (sec) equivalent to Compare to Reference ROI. Template Effective Date: 26 Mar 2025 | QR700020784 27 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Result table Template Effective Date: 26 Mar 2025 | QR700020784 28 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve SIEMENS Healthineers Result Table (I) A A TC1 In the Result segment, you can toggle between Dynamic TC1 Min / Max: 145.00 /530.00 Min / Max: 34.00 /748.00 Mean/SD: 248.67 /50.10 Mean/SD: 434.78 /146.97 Area: 1.02 cm2 Area: 1.02 cm2 the curves and the table using the left and/or Sum: 24867.00 Sum: 43478.00 100 Pixels ............ 100 Pixels right lateral arrows on that segment. TC4 TC4 Min / Max: 64.00 /1010.00 Min / Max: -110.00 /748.00 Mean/SD: 377.54 /207.09 Mean/SD: 280:46/178.45 Area: 4.57 cm2 Area: 4.57 cm2 R Sum: 166873.00 Sum: 123962.00 R 442 Pixels 442 Pixels 1 • The first column of the table shows the x-axis values, such as Normal Time, Trigger Time, or Image No., based on the Result Table x-axis selection of the curves. 2 1 2 • The other column shows the values for the different ROIs, which are the y-axis Mean Name 800 1.02 cm2 TC2 TC3 2.05 cm2 TC4 2.46 cm2 4.57 cm2 700 Normal Time values. In addition, they provide the area sec Mean Mean Mear Mean 600 0.00 248.67 288.47 278.52 377.54 of each TC-ROI. 500 135.32 593.88 582.82 619.96 552.45 R 400 230.65 683.45 713.39 734.45 658.00 300 325.97 740.95 770.98 771.48 706.02 200 100 Checking all TC-ROIs in the Tabular 0 0 50 100 150 200 250 300 350 View Time Offset: 0 sec Normal Time (sec) Result Table 1 of 1 1 Use the right lateral arrow to check the values of all the TC-ROIs across different time points. Template Effective Date: 26 Mar 2025 | QR700020784 29 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve SIEMENS Healthineers Result Table (II) 1 3 The values provided in the Result Table are: Name 1.02 cm2 TC3 TC1 TC3 Area 2.46 cm2 2.05 cm2 TCA Name 4.57 cm2 Area 1.02 cm2 TC2 2.46 cm2 2.05 cm2 TCA 4.57 cm2 1 • For the Mean mode: Normal Time Mean Mean Mean Mean Normal Time Mean Mean Ratio % Mean Ratio % sec sec Mean Ratio % 0.00 248.67 288.47 278.52 377.54 0.00 248.67 288.47 116.01 278.52 112.00 377.54 151.82 • The mean value of all pixels of each 135.32 593.88 582.82 619.9 552.45 135.32 593.88 582.82 18.14 619.96 04.39 552.45 93.02 TC-ROI. 230.65 683.45 713.39 734.45 658.00 230.65 583.45 713.39 104.38 734.45 107 46 658.00 96.28 325.97 740.95 770.98 771.48 706.02 325.97 740.95 770.98 104.05 771.48 104.12 706.02 95.29 2 • For the Mean (%) mode: • The mean value of all pixels of each TC-ROI. Result Table 1 of 1 Result Table 1 of 2 • The mean normalized value of all 2 pixels of each TC-ROI as Mean (%). Name TC1 Name 1.02 cm2 TC2 2.46 cm2 TC3 TC4 Area 2.05 cm2 4.57 cm2 3 • For the Ratio (%) mode: Normal Time Mean Mean % Mean Mean % Normal Time Mean vean % Mean Mean 9 sec sec 0.00 248.67 0.00 288.47 0.00 0.00 278.52 0.00 377.54 0.00 • The mean value of all pixels of each 135.32 593.88 138.82 582.82 102.04 135.32 619.96 122.59 552.45 46.33 TC-ROI. 230.65 683.45 174.84 713.39 147.30 230.65 34.45 163.70 658.00 74.29 325.97 740.95 197.97 70.98 167.27 325.97 771.48 177.00 706.02 87.00 • The mean normalized value of all pixels of each TC-ROI as Ratio (%), except for the TC-ROI used as reference, which value is 100%. Result Table 1 of 2 Result Table 2 of 2 Template Effective Date: 26 Mar 2025 | QR700020784 30 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Saving results Template Effective Date: 26 Mar 2025 | QR700020784 31 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve SIEMENS Healthineers Saving results TimeCurve 1 Dynami A To document the results of the TimeCurve TC1 TC1 Min / Max: 269.00 /955.00 Min / Max: 110.00/742.00 O Mean/SD: 740.95 /122.15 Mean/SD: 492.28/121.70 Area: 1.02 cm2 Area: 1.02 cm2 evaluation, you must save the results as Sum: 74095.00 Sum: 49228.00 TC-Circle TC-Pixel TC TC- 100 Pixels 100 Pixels Lens Freehand Snapshot snapshots. Basic Breast 1 • In the TimeCurve panel, click the TC -Snapshot icon. Min / Max: 269.00 /1007.00 Min / Max: -115.00 /742.00 Mean/SD: 706:02 /133.61 Mean/SD: 328.48 /197.61 Area: 4.57 cm2 Area: 4.57 cm2 Sum: 145186.00 Sum: 312059.00 442 Pixels 442 Pixels 2 • In the Series panel, a series of snapshots is created. The series contains the resulting curves and all frames with Mean (%) 200 measurements. 175 150 125 Results Time Curve 100 1 When you save the results of the 50 TimeCurve, the created series receives the name Results Time Curve . 50 100 150 200 350 Time Offset: 0 sec Normal Time (sec) # Series Name No automatic creation of findings 1/17/2022 2:08 PM The TimeCurve tool does not create any MR, Carcinoma_Dixon 2 B17ch finding or result series automatically H. 1045 Results Time Curve when you perform a measurement. Template Effective Date: 26 Mar 2025 | QR700020784 32 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Technical details Template Effective Date: 26 Mar 2025 | QR700020784 33 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers TC-Layout selection TimeCurve × Dynamic TC1 When the TimeCurve opens, the application TC1 Min / Max: 269.00 /955.00 Min / Max: 110.00 /742.00 Mean/SD: 740.95 /122.15 Mean/SD: 492.28/121.70 O Area: 1.02 cm2 Area: 1.02 cm2 automatically selects a TC-Layout. Sum: 74095.00 Sum: 49228.00 100 Pixels 100 Pixels TC-Circle TC-Pixel TC- TC- Lens Freehand Snapshot For non-MR data, it selects the Basic layout (2x1). Basic Breast TC4 Min / Max: 269.00/1007.00 Min / Max: -115.00 /742.00 Mean/SD. 328.48/197.61 For MR data, it selects a layout based on the Mean/SD: 706:02/133.61 Area: 4:57 cm2 Area: 4.57 cm2 Sum: 145186.00 Brain Sum: 312059.00 442 Pixels 442 Pixels presence of brain, breast or prostate in specific Breast DICOM tags. These tags include: • Prostate Body Part Examined (0018,0015) Mean (9%) 1 • Study Description (0008,1030) Multi parametric 175 150 • Patient’s Name (0010,0010) 125 • Patient Comments (0010,4000) 100 75 The corresponding layout (Brain, Breast or Basic layout Prostate) is then selected. If the application (2x1) cannot find any of those strings, the Multi 50 100 150 200 250 300 350 Time Offset: 0 sec Normal Time (sec) parametric layout is selected. You can manually change the layout at any time Dedicated MR layouts (2x2) by selecting a different option. Template Effective Date: 26 Mar 2025 | QR700020784 34 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers Dynamic data selection Dynamic data used for the dynamic Dynamic When the TimeCurve opens, the application TC1 Min / Max: 269.00 /955.00 Min / Max: 110.00 /742.00 Mean/SD: 740.95 /122.15 Mean/SD: 492.28/121.70 evaluation automatically selects one of the available Area: 1.02 cm2 Area: 1.02 cm2 Sum: 74095.00 Sum: 49228.00 100 Pixels 100 Pixels dynamic data (4D data). Those data are loaded in the top left image R R segment, which is labeled as Dynamic, indicating that the results are calculated from those data. TC4 TC4 Min / Max: 269.00/1007.00 Min / Max: -115.00 /742.00 Mean/SD: 706.02/133.61 Mean/SD: 328.48/197.61 Area: 4.57 cm2 Area: 4:57 cm2 Sum: 312059.00 Sum: 145186.00 442 Pixels The selection of the dynamic data is based on: 442 Pixels • The sequence type: • Dynamic acquisitions (fl3d, vibe...) Mean (%) • Dynamic subtractions (fl3d, vibe...) 200 • Perfusion data (ep2d_perf…) 175 • Diffusion data (ep2d_se, resolve…) 150 125 • The acquisition order. 100 75 You can manually update the dynamic data at 50 25 any time by dragging and dropping the desired data from the Series panel to the Dynamic 50 100 150 200 250 300 350 Time Offset: 0 sec Normal Time (sec) segment. Template Effective Date: 26 Mar 2025 | QR700020784 35 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers Image segments in TC-Layouts: Basic Single monitor configuration Dual monitor configuration Dynamic Result segment Dynamic Result segment Template Effective Date: 26 Mar 2025 | QR700020784 36 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers Image segments in TC-Layouts: Brain Single monitor configuration Dual monitor configuration T1 weighted T1 weighted Dynamic DWI DWI pre-contrast Dynamic pre-contrast (native) (native) lowest b-value highest b-value FLAIR Result segment FLAIR Result segment ADC maps SPACE or MPRAGE or any sagittal Template Effective Date: 26 Mar 2025 | QR700020784 37 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers Image segments in TC-Layouts: Breast Single monitor configuration Dual monitor configuration Dynamic Subtractions of the Subtractions of the Dynamic Dynamic Dynamic T2 weighted Non-fat sat. Subtractions of the Subtractions of the Dynamic Result segment Dynamic Result segment ADC maps DWI (Display Type = MIP) (Display Type = MIP) highest b-value Template Effective Date: 26 Mar 2025 | QR700020784 38 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers Image segments in TC-Layouts: Prostate Single monitor configuration Dual monitor configuration Dynamic T2 weighted Dynamic T2 weighted T2 weighted T2 weighted transversal transversal sagittal coronal DWI highest b-value Result segment DWI highest b-value ADC maps Result segment Lymph nodes Template Effective Date: 26 Mar 2025 | QR700020784 39 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 TimeCurve: Technical details SIEMENS Healthineers Image segments in TC-Layouts: Multi parametric Single monitor configuration Dual monitor configuration T1 weighted Dynamic Subtractions of the Subtractions of the T1 weighted Dynamic Dynamic Dynamic transversal or FLAIR pre-contrast or STIR (native) DWI Result segment DWI ADC maps Any sagittal or highest b-value highest b-value coronal Result segment Template Effective Date: 26 Mar 2025 | QR700020784 40 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025 SIEMENS Healthineers Please note that this learning material is for training purposes only. For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Please note: Some functions shown in this material are optional and might not be part of your system. Certain products, product-related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration-dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Siemens Healthineers Headquarters Siemens Healthineers AG Siemensstr. 3 91301 Forchheim, Germany Phone: +49 9191 180 siemens-healthineers.com Template Effective Date: 26 Mar 2025 | QR700020784 41 Job Aid Effective Date: 15 May 2025 | QR700023281 Published by Siemens Healthineers AG I © Siemens Healthineers, 2025