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syngo MR XA70A - What's New List MAGNETOM Avanto Fit BM, Skyra Fit BM, Sola Fit, & Viato.Mobile

The What's new list provides you an overview of features and options coming with the software XA70A.
Target group: All users.
Product relevance: MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile

MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, Including MAGNETOM Sola Fit, MAGNETOM Viato.Mobile AdvanceNow Advance your magnetic resonance imaging syngo MR XA70A – What’s new siemens-healthineers.us/magnetic-resonance-imaging SIEMENS Healthineers Dear MAGNETOM user, We are pleased to announce the arrival of our latest MRI scanner software, syngo MR XA70A. This new software version includes comprehensive improvements to the existing scanner functionalities and provides access to exciting new features. You have received this document to accompany the installation of the syngo MR XA70A software on your MAGNETOM scanner(s). Scanners qualified for this update include the following 1.5 and 3T systems: • MAGNETOM Avanto Fit, A BioMatrix System • MAGNETOM Skyra Fit, A BioMatrix System • MAGNETOM Sola Fit • MAGNETOM Viato.Mobile This document provides a comprehensive overview of the new features and software improvements that are incorporated in the syngo MR XA70A software. Please note that the features mentioned in this document are not available for MAGNETOM Avantofit and MAGNETOM Skyrafit classic editions, but refer ONLY to our MAGNETOM Avanto Fit BioMatrix and MAGNETOM Skyra Fit BioMatrix systems. If you are unsure which system you have, then please speak to your local Siemens Healthineers team who can assist you. We are continuously striving to improve the quality of our products and sincerely believe that this new software version will further improve your daily work with your MAGNETOM scanner. Sincerely yours, Your Siemens Healthineers MR team AdvanceNow, the long-term update and upgrade service from Siemens Healthineers, is your digital strategy enabling you to be constantly up to date. It offers continuous access to innovations and state-of-the-art cybersecurity and allows efficient and long-lasting equipment performance by constantly and proactively providing updates and cybersecurity patches, online. To enable you to benefit from advancements in intelligent imaging and deliver efficient precision medicine, system software upgrades are offered as soon as they become available and computing hardware is replaced as soon as required. Contents Contents 1. New sequences, protocols, and applications 4 1.1. myExam Implant Suite 4 1.2. myExam 3D Camera 5 1.3. Deep Resolve Gain 6 1.4. Deep Resolve Sharp 7 1.5. Deep Resolve Boost 8 Deep Resolve for TSE 8 Deep Resolve for EPI diffusion 9 Deep Resolve for HASTE 10 1.6. Deep Resolve Swift Brain 11 1.7. Open Recon 12 1.8. Physiologging 13 1.9. BioMatrix Beat Sensor 14 1.10. Single-voxel spectroscopy edit 14 1.11. Needle Intervention add-in 14 1.12. HASTE Interactive Realtime 15 1.13. BLADE diffusion 15 1.14. HASTE diffusion 15 1.15. AutoMate Cardiac 16 1.16. 3D WholeHeart Pro 17 1.17. myExam Advanced Angio Assist 18 1.18. myExam Brain Autopilot and myExam Knee Autopilot 19 1.19. Patient Registration at the Select&GO 20 2. New coils 21 2.1. BioMatrix Head/Neck 20 tiltable coil with CoilShim 21 3. Improvements to sequences, protocols, and applications 22 3.1. Complex averaging 22 3.2. Dual-polarity GRAPPA 22 3.3. Inline filter 23 3.4. Lock TR and FA for BOLD imaging 24 Overview 25 3 syngo MR XA70A – What’s New 1. New sequences, protocols, and applications 1.1. myExam Implant Suite Included with AdvanceNow Available for: MAGNETOM Sola Fit and MAGNETOM Viato.Mobile Category: Standard feature Pre-requisites: None Restrictions: None What is myExam Implant Suite? displayed any time during the scan process. Furthermore, myExam Implant Suite supports MRI examinations of users can enter a scan time limit specified by the implant patients with MR Conditional implants. manufacturer, and receive timely notifications before the timer expires. Comments to be archived with the study It offers the radiographer an easy way to individually set can also be entered here. SAR limits (for both head and whole body) or B1+rms limits for patients with implants who require MRI examinations. Highlights and benefits: The system ensures that these limits are not exceeded • Allows scanning of patients with MR Conditional during the examination, protecting both the patient implants (active and passive implants). and the implant. This makes it possible to offer the • Supports limits for SAR or B1+rms. benefits of MRI to a growing patient population with • MR Conditional implants. Included in the patient registration process. • Defined limits are stored in the DICOM structured Concept explanation report object. • The myExam Implant Suite functionality is activated Allows additional comments to be stored in the DICOM during patient registration. The system provides an report object. additional user interface for entering maximum B1+ rms • Provision of SAR-adapted examination sequences in or SAR (head and whole body) values when registering the SIEMENS protocol tree for specific body regions implant patients. These limits are monitored and can be Predefined Scheduler Included in the SAR-reduced Limits for MR Conditional Implant Examination Information patient registration protocols available Possibility for Intuitive entry of additional implant-specific comments Program Selection SAR or B1+ rms Per Transmit Mode limits Body Part and Laterality Patient Orientation IT 4 syngo MR XA70A – What’s New 1.2. myExam 3D Camera Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: None What is myExam 3D Camera? Highlights and benefits: myExam 3D Camera automates patient positioning 1. AutoPositioning making it more efficient, accurate, and reproducible. Its Using infrared measurements, myExam 3D Camera AutoPositioning feature captures the patient’s shape and recognizes body contours and the position of the various position on the table in three dimensions. myExam 3D body parts, e.g., position of the elbow, wrist or hand. Camera extends the automatic positioning capabilities of AutoPositioning integrates these measurements with the BioMatrix Select&GO by additional body regions and coils. data from the Select&GO touch display. The AI-trained In addition, AutoRegistration is designed to streamline algorithm of myExam3D Camera automatically detects and help safeguard accurate patient registration based body landmarks and positions the relevant body parts in on height and weight. the isocenter of the MRI scanner without the need to use the table measurement scale or the positioning laser. This can make positioning up to 48%1 faster compared with a manual workflow without the help of the camera allowing for accurate and consistent positioning – even – with flexible Contour coils. The myExam 3D Camera feature supports the following SIEMENS patient orientations: • Supine • Prone • Head First MAGNETOM Sola Fit • Feet First Further information: Check out the myExam 3D Camera workflow video on the following website: 7 siemens-healthineers.us/magnetic-resonance- imaging/technologies-and-innovations/my-exam- companion 1 Data on file. 5 syngo MR XA70A – What’s New 1.3. Deep Resolve Gain Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature, part of Deep Resolve Discover and Deep Resolve Pro Pre-requisites: None Availability: Deep Resolve Gain is available for SE, TSE, and TSE_DIXON What is Deep Resolve Gain? Highlights and benefits: Deep Resolve Gain is our solution for intelligent • Deep Resolve Gain addresses local noise variations denoising, addressing local noise variations. Image noise arising from coil array geometries and parallel usually is not uniformly distributed in MR images. This is imaging techniques. due to coil array geometries and acceleration techniques • Individual noise maps are generated from the acquired such as parallel imaging. These local variations cannot be raw data and fed into the reconstruction process. addressed by standard image filters. Deep Resolve Gain • uses individual noise maps in the reconstruction process Areas in the image with low SNR can be denoised to reduce noise where it is most needed in the image. more effectively. Deep Resolve Gain can be used to reduce image acquisition • Deep Resolve Gain can be applied from head to toe times. There are mainly two ways this can be achieved: and is not limited to certain coils. Deep Resolve Gain can be used to mitigate noise when reducing the number of averages in the acquisition, or when increasing acceleration factors such as PAT. 1aaaa3592 T2 TSE conventional reconstruction T2 TSE with Deep Resolve Gain 6 syngo MR XA70A – What’s New 1.4. Deep Resolve Sharp Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature, part of Deep Resolve Discover and Deep Resolve Pro Pre-requisites: None Availability: SE, TSE, TSE_DIXON, EPI diffusion, HASTE What is Deep Resolve Sharp? Highlights and benefits: Deep Resolve Sharp is a novel image reconstruction • Deep Resolve Sharp uses a neural network to increase technology to increase resolution and sharpness in the the sharpness of the reconstructed images. resulting images. The deep neural network at the core • The matrix size can be doubled along each in-plane axis. of Deep Resolve Sharp generates a high-resolution image • from low-resolution input data. The network was trained Robust results are ensured by incorporating the on a large number of pairs of low-resolution and high- originally acquired raw data into the reconstruction. resolution data. • Deep Resolve Sharp is used in combination with Deep Resolve Gain or Deep Resolve Boost to obtain sharper As the training data for Deep Resolve Sharp covered a wide images faster. range of anatomies, the reconstruction network can be • applied to all body regions. Deep Resolve Sharp can Deep Resolve Sharp can be applied from head to toe increase the matrix size by a factor of up to two along and is not limited to certain coils. both in-plane axes, resulting in substantially increased image sharpness. Deep Resolve Sharp can also be used to reduce acquisition times: Images can be acquired with reduced phase resolution; the resolution can then be recovered when reconstructing the images with Deep Resolve Sharp. 1aaaa3588 T2 TSE, conventional reconstruction T2 TSE, Deep Resolve Gain & Sharp 7 syngo MR XA70A – What’s New 1.5. Deep Resolve Boost Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature, part of Deep Resolve Pro Pre-requisites: High-end computing Availability: TSE, EPI diffusion and HASTE Deep Resolve for TSE What is Deep Resolve Boost? Highlights and benefits: Deep Resolve Boost takes deep learning reconstruction to • Deep learning reconstruction with effective denoising the next level. It enables previously inaccessible parallel • Three levels selectable for the denoising strength imaging acceleration. This is made possible by our first raw • data-to-image deep learning reconstruction. The neural Deep Resolve Boost outperforms Deep Resolve Gain network behind Deep Resolve Boost enables effective in its denoising capability. denoising that improves the visual signal-to-noise ratio • Enables parallel imaging factors previously inaccessible of the images. The deep learning reconstruction used in in MR imaging. Deep Resolve Boost achieves stronger denoising than • Significantly reduces scan times where TSE is Deep Resolve Gain, and the denoising strength can be a mandatory imaging sequence. adapted by choosing from three levels. With this, Deep • Deep Resolve Boost is compatible with SMS TSE and Resolve Boost will significantly cut scan times from head EPI, an exclusive feature of Siemens Healthineers. to toe without compromising on image quality. Deep Resolve Boost can be combined with SMS, rendering this the industry’s first k-space to image-space deep learning reconstruction that can be combined with SMS. PD TSE fs T1 TSE PAT 3, SMS 2, Deep Resolve PAT 2, SMS 2, Deep Resolve PAT 2, SMS 2, Deep Resolve PAT 3, SMS 2, Deep Resolve 0.2 x 0.2 x 3.0 mm³ 0.2 x 0.2 x 3.0 mm³ 0.2 x 0.2 x 3.0 mm³ 0.2 x 0.2 x 3.0 mm³ TA 0:32 min TA 0:45 min TA 0:49 min TA 0:49 min Total scan time: 2:23 min 1aaaa3997 T2 TSE conventional reconstruction 8 syngo MR XA70A – What’s New Deep Resolve for EPI diffusion Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile, and MAGNETOM Skyra Fit Category: Purchasable feature, part of Deep Resolve Pro Pre-requisites: High-end computing Restrictions: None What is Deep Resolve for EPI diffusion? With Deep Resolve Boost for EPI Diffusion, you can Deep Resolve Boost and Deep Resolve Sharp are now improve image quality and lesion conspicuity, and reduce available for the EPI diffusion sequence. Deep Resolve the acquisition time of diffusion scans. Boost takes deep learning reconstruction to the next level. It enables previously inaccessible parallel imaging Highlights and benefits: acceleration. This is made possible by our first raw data- • Deep Resolve boosts acquisition speed and image to-image deep learning reconstruction. The neural sharpness. network behind Deep Resolve Boost enables effective • Three levels selectable for the denoising strength denoising that improves the signal-to-noise ratio of the • images. Deep Resolve Sharp is a novel image Deep Resolve for EPI can be used with SMS, thus reconstruction technology to increase the sharpness of combining the best of two worlds. the resulting images. The deep neural network at the • Perform a biparametric PI-RADS 2.1 prostate exam core of Deep Resolve Sharp generates a high-resolution in less than 6 minutes with Deep Resolve. image from low-resolution input data. T2w TSE with Deep Resolve DWI with ZOOMitPRO and Deep Resolve b800 Calc b2000 ADC 1:06 min 0:56 min 0:52 min 2 min 9 syngo MR XA70A – What’s New Deep Resolve for HASTE Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile, and MAGNETOM Skyra Fit Category: Purchasable feature, part of Deep Resolve Pro Pre-requisites: High-end computing Restrictions: None What is Deep Resolve for HASTE? Highlights and benefits: Deep Resolve Boost and Deep Resolve Sharp are now • Enables higher parallel imaging factors, resulting available for the HASTE sequence. Deep Resolve Boost in substantially reduced scan times. takes deep learning reconstruction to the next level. • Enables shorter echo train durations and reduced It enables previously inaccessible parallel imaging T2 blurring. acceleration. This is made possible by our first raw data-to- • image deep learning reconstruction. The neural network Reduces the acquisition time of a body T2-weighted behind Deep Resolve Boost enables effective denoising scan by up to 90%, in a single breath-hold. that improves the signal-to-noise ratio of the images. Deep Resolve Sharp is a novel image reconstruction technology to increase the sharpness of the resulting images. The deep neural network at the core of Deep Resolve Sharp generates a high-resolution image from low-resolution input data. With Deep Resolve, you can achieve excellent image quality, diagnostic confidence, and lesion detection for a HASTE body scan. Multi Breath-hold Single Breath-hold O T2 HASTE T2 HASTE, PAT 4, Deep Resolve 1.2 x 1.2 x 6.0 mm³ 0.6 x 0.6 x 5.0 mm³ TA 1:33 min TA 0:28 min 1aaaa4574 10 syngo MR XA70A – What’s New 1.6. Deep Resolve Swift Brain Available for: MAGNETOM Skyra Fit Category: Purchasable feature, part of Deep Resolve Pro Pre-requisites: High-end computing Restrictions: None What is Deep Resolve Swift Brain? Highlights and benefits: Deep Resolve Swift Brain is an ultra-fast brain protocol, • Ultra-fast brain examination with a multishot EPI leveraging the fastest available imaging sequence, EPI, implementation exclusive to Siemens Healthineers together with deep learning reconstruction to push supported by deep learning reconstruction. acceleration to the edge. The protocol consists of five • Five resulting contrasts: T1, T2, T2*, T2 dark-fluid contrasts: T1, T2, T2*, T2 dark fluid, and diffusion. While and diffusion T1 is based on a fast GRE imaging sequence, the remaining • contrasts are multishot EPI-based. Multishot EPI together Net scan time < 2 minutes with a new static field correction minimizes geometric • Total table time including prescans, adjustments, distortions that are intrinsic to EPI imaging. Within this and imaging < 5 minutes. multishot EPI approach, T2 and T2* are acquired • New static field correction to further minimize simultaneously by an EPI implementation exclusive to EPI-intrinsic geometric distortions; available for all Siemens Healthineers, further accelerating this protocol. EPI sequences with purchase of a Deep Resolve Swift Multishot EPI-based T2 dark fluid reduces imaging times Brain license. substantially compared with standard TSE imaging and offers true DarkFluid (FLAIR) contrast due to magnetization transfer preparation. The highest image quality is ensured by deep learning reconstruction to push the limits of parallel imaging acceleration. The unique combination of multishot EPI imaging and deep learning reconstruction enables net scan times of less than two minutes. The total table time including prescans and adjustments can be less than five minutes with this protocol. 11 syngo MR XA70A – What’s New 1.7. Open Recon Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile, and MAGNETOM Skyra Fit Category: Optional, free of charge Pre-requisites: None Restrictions: None What is Open Recon? Highlights and benefits: Open Recon is a developer-friendly open digital interface • Open platform design supports key interactions for co-creation and knowledge exchange with partners between Siemens Healthineers and partners. and researchers. The partner application runs within • Third-party image reconstruction techniques and a container directly on the MaRS and is seamlessly machine learning directly at the scanner integrated into the image reconstruction chain. It appears • as an additional tab on the “Inline” card and provides Inline reconstruction can facilitate clinical evaluation convenient access to options supported by Open Recon. • Convenient access via new tab on the “Inline” card Results are displayed in the user interface and will appear • Simplified reconstruction development for research in the DICOM database. With XA70A, researchers can now emit data from any given point in the image reconstruction pipeline, i.e., even raw data can be directed to the containerized reconstruction. Similarly, the processed data can be injected back into the standard image reconstruction pipeline at any given point. USER >> head >> Brain Assist >> program >> t1_qtse_dark-fluid_sag_p2 ? X General @ 4:38 min Auto 0.7x0.7x4.0 mm3 1.00 Protocol Parameters Routine Contrast Resolution Geometry System Physio Inline Sequence Voice Commands Execution Subtraction MIP Composing Open Recon Image Management Algorithm myRecon 1 Auto Load Copy References Preview Preset denoise Parameter 1 Setting A Free Text denoise denoise-enhanced-level1 ... Parameter 2 Setting B mg denoise-enhanced-level2 denoise-enhanced-level3 Option 1 super-resolution Option 2 smooth-super-resolution edge-super-resolution super-resolution-gre-mpr super-resolution-dwi 12 syngo MR XA70A – What’s New 1.8. Physiologging Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile, and MAGNETOM Skyra Fit Category: Optional, free of charge Pre-requisites: Respiratory belt, ECG, PMU Restrictions: None What is Physiologging? Highlights and benefits: Physiologging enables the extraction of physiological data. • Timestamped physiological data for easier Time stamps on the physiological data allow easy synchronization with fMRI data synchronization of physio data to corresponding fMRI data • Recording can be started via a checkbox on the user acquired with either EPI BOLD or EPI PACE. This helps interface (Physio -> Signal tab). researchers to correct fMRI data for physiological motion • and noise. All parameters recorded by internal physiological Physio data are stored as a separate DICOM file, which sensors (such as BioMatrix Respiratory Sensors, respiratory can also be archived. belts, ECG, pulse sensors, and BioMatrix Beat Sensors) are then available in a convenient data format for further offline processing. The physio curves are stored in a separate DICOM file with their timestamps. 00:32 Access time-synced sensor data for fMRI scans as part of the DICOM study Sample code available for extraction Available for EPI BOLD & PACE Physiologging 13 syngo MR XA70A – What’s New 1.9. BioMatrix Beat Sensor Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Standard feature with BioMatrix Body 18 coil Pre-requisites: BioMatrix Body 18 coil Restrictions: None What is BioMatrix Beat Sensor? Highlights and benefits: The Beat Sensor is a unique breakthrough technology of • The major benefit of the Beat Sensor is that it eliminates Siemens Healthineers, which enables a complete cardiac the need to place electrodes on the patient and hence MRI exam without ECG. The Beat Sensor uses the heart’s can speed up the workflow for CMR exams. own beating motion as the triggering source, unlike ECG, • Technologists no longer have to spend time shaving which only indirectly measures the onset of cardiac motion the patient’s chest, using cleaning gel, and placing by detecting the electrical activity of the heart. electrodes. • Beat Sensor triggering can also improve the patient experience, especially for patients who have sensitive skin (e.g., allergic to cleaning gel) and/or feel uncomfortable with electrode placement. • Hospitals can save on supplies and reduce plastic waste. 1.10. Single-voxel spectroscopy edit Available for: MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: None Restrictions: None What is Single-voxel spectroscopy edit? Single-voxel spectroscopy with editing pulses (SVS Edit) below other spectral peaks. The editing pulse allows a extends the possibility of SVS to detect J-coupled two-step measurement: One SVS measurement with and metabolites such as GABA. In a normal spectrum, these one without the editing pulse. By subtracting the two signals are not easily recognizable as they are hidden spectra, the J-coupled metabolites can be visualized. 1.11. Needle Intervention add-in Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: Advanced Interactive Realtime Restrictions: In-room monitor and in-room modality (e.g., foot switch) are highly recommended What is Needle Intervention add-in? Highlights and benefits: This add-in provides a user interface for workflow • This add-in combines different existing system improvement of MR-guided needle interventions. functionalities to simplify the workflow. It supports planning a needle trajectory, laser-based localization of the entry point, as well as automatic slice positioning. 14 syngo MR XA70A – What’s New 1.12. HASTE Interactive Realtime Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: Advanced Interactive Realtime Restrictions: None What is HASTE Interactive Realtime? The Advanced Interactive Realtime license now also interactively, e.g., slice position and orientation, during includes the HASTE Interactive sequence, allowing the acquisition. the user to change a subset of imaging parameters 1.13. BLADE diffusion Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: None Restrictions: None What is BLADE diffusion? Highlights and benefits: BLADE diffusion is a multishot TSE-based imaging • New non-EPI based diffusion functionality based on technique combined with BLADE trajectories, offering a BLADE TGSE sequence diffusion-weighted imaging with reduced sensitivity to • No geometric distortions in challenging areas with B0 inhomogeneity and reduced image blurring, e.g. in large susceptibility changes the middle ear, due to the transition from air to tissue. • The non-EPI-based acquisition technique offered with SMS support for BLADE diffusion is an exclusive feature the new BLADE diffusion sequence is suitable for from Siemens Healthineers diffusion-weighted imaging in such areas. It is possible to combine BLADE diffusion with GRAPPA and SMS (part of the Turbo Suite Excelerate package). 1.14. HASTE diffusion Included with AdvanceNow Available for: MAGNETOM Skyra Fit Category: Standard feature Pre-requisites: None Restrictions: None What is HASTE diffusion? Literature: HASTE diffusion is a non-EPI based diffusion sequence to [1] De Foer B. et al: The value of single-shot turbo spin-echo reliably detect diffusion-restrictive abnormalities such as diffusion-weighted MR imaging in the detection of middle ear cholesteatomas [1–3]. cholesteatoma; Neuroradiology 49:841-848 (2007) [2] Fan X. et al.: The value of turbo spin-echo diffusion weighted imaging apparent diffusion coefficient in the diagnosis of Highlights and benefits: temporal bone cholesteatoma; Clin Radiol 74:977.e1-977.e7 (2019) • Comprehensive diffusion portfolio with single-shot EPI, [3] Henninger B. and Kremser C.: Diffusion weighted imaging for the RESOLVE, BLADE, and HASTE diffusion detection and evaluation of cholesteatoma; World J Radiol 9:217- 222 (2017) 15 syngo MR XA70A – What’s New 1.15. AutoMate Cardiac Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile, and MAGNETOM Skyra Fit Category: Free of charge Pre-requisites: Standard Restrictions: None What is Cardiac AutoMate? Highlights and benefits: AutoMate Cardiac minimizes residual complexities in a • AutoPositioning to ensure that the heart is clinical cardiac examination with further optimization the magnet isocenter. suggestions. It is an AI-based automated workflow that • Auto Resting Phase detection to optimally acquire supports the set-up of accurate scan parameters using data during the cardiac resting phase. software features from the Cardiac Suite. The workflow • helps to improve intraoperator variations and provide Auto TI proposal to provide optimal inversion time standardization across all cardiac MRI examinations. for cardiac delayed enhancement measurements. ISAB Settings for Tiasue Characterization Auto 1 Parameters 8 542 mis < Auto 2 50 9 10-10-10mm + 1.14 Line Firsting Ptuse Paramursres Inversion Time Source protocol Auto TI scout Data Window Source protocol cine_Indki retro_es.2_shot_4ch Und 787 - Region of interest Right coronary artery 420 TI Suggestion TI Offset Douala Window Riesling Pose Saggition - Motion per phase 16 syngo MR XA70A – What’s New 1.16. 3D WholeHeart Pro Available for: MAGNETOM Avanto Fit, MAGNETOM Sola Fit, MAGNETOM Viato.Mobile, and MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: High-end computing, Advanced Cardiac incl. PSIR, Compressed Sensing Cardiac Cine Restrictions: BioMatrix Spine 32 and Body 18 coils with a system configuration of [204x48] or above. What is 3D WholeHeart Pro? Highlights and benefits: 3D WholeHeart Pro enables: • Image navigator with 100% acceptance rate and predicable scan times (3-10 minutes; Data on file) • Coronary artery visualization • New sampling pattern VD-CASPR with non-rigid motion • Imaging of the complex anatomies of the thorax (e.g., in congenital heart disease) correction, which provides high overall undersampling factors and enables artifact-free respiratory images. • Scar tissue characterization of ischemic and non-ischemic cardiomyopathies • DIXON imaging for robust fat and water separation, • Imaging assessment of myocardial lesions improving visualization of the coronary arteries. for electrophysiology procedures, pre- and post- intervention RCA LAD D1 LCX 3D Volume-Rendered CMRA DI RCA CCTA LAD Images courtesy of Reza Hajhosseiny, Aurelien Bustin, Imran Rashid, Gastao Cruy, Ronak Rajani, Claudia Prieto, Rene M. Botnar et al.: Clinical comparison of sub-mm high-resolution non-contrast coronary MRA against coronary CTA in patients with low-intermediate risk of CAD: A single center trial. J Cardiovasc Magn Reson. 2021;23(1):57. 17 syngo MR XA70A – What’s New 1.17. myExam Advanced Angio Assist Available for: MAGNETOM Avanto Fit and MAGNETOM Skyra Fit Category: Purchasable feature Pre-requisites: myExam Angio Assist Restrictions: None What is myExam Advanced Angio Assist? After planning is complete, the angio precontrast data myExam Angio Advanced Assist is a semiautomated acquisition is executed for all planned stations. With the workflow for peripheral MR angiography examinations Care Bolus step, the arrival of the contrast agent is with step-by-step guidance throughout the exam. This manually or automatically detected. Once the contrast workflow support feature offers clear planning for all agent is detected, the angio postcontrast measurement multi-station angiography exams by enabling planning in is performed in accordance with the precontrast the Graphical Slice Positioning (GSP) user interface for all measurement. Alternatively, the Test Bolus workflow stations in one common planning step. This new Assist can be used. Finally, an optional dynamic CE MRA workflow uses the Test Bolus and Care Bolus functionality (TWIST) measurement can be performed. to optionally track the bolus’s arrival in the vessels. Highlights and benefits: myExam Angio Advanced Assist provides workflow • support for peripheral MR angiography exams. After Automation and guidance for robust peripheral performing an overview scan, the relevant peripheral MRA exams vessels and the aorta are localized. Then planning of • Easy planning with coverage boxes, overlap clearly the actual angiography measurement is performed visible using the Angio Advanced Planning add-in, which helps • Individual parametrization plan all stations (abdomen, legs, feet) together in the GSP. Angio Assist Advanced Angio Advanced Patien ... V Care Bolus Feet first - Position 20cm / 7in above feet FastView 00:35 Whole Body FastView Vessel Scout yes vessel_scout O O Abdomen 02:19 Abdomen Generic Views localizer_aorta 00:31 + Generic Views angio_f13d_cor_pre 00:39 Angio Advanced Planning Check pre images, prepare injector Legs Legs Care Bolus 01:21 Care Bolus angio_f13d_cor_post 00:39 1 TWIST feet yes Basic Decision Feet WIST feet Feet yes angio_twist_cor_iso feet 02:03 Generic Views 18 syngo MR XA70A – What’s New 1.18. myExam Brain Autopilot and myExam Knee Autopilot Included with AdvanceNow Available for: MAGNETOM Avanto Fit Category: Standard feature Pre-requisites: None Restrictions: None What is myExam Autopilot? Highlights and benefits: myExam Autopilot for Brain and Knee helps users to • Automates exams to support novice users. automate intelligently. The automated scanner software • Scan in high quality with just a simple click. allows less skilled clinical staff to perform brain and knee • examinations in high quality. By using automation and AI, myExam Knee and Brain Autopilot cover >40% of all it eliminates burdensome routine tasks for all technolo- MRI exams1. gists. myExam Knee Autopilot and myExam Brain Autopilot provide automation such as AutoPosition, AutoAlign, AutoCoverage, Inline MPRs, and the flexibility of customization for site-specific standards of care. Predefined protocols allow users to scan with minimal manual interactions. Users can switch to myExam Assist at any time to further personalize scan settings on the fly. 000000000 19 syngo MR XA70A – What’s New 1.19. Patient Registration at the Select&GO Available for: MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, MAGNETOM Sola Fit and MAGNETOM Viato.Mobile Category: Optional feature Pre-requisites: None Restrictions: None With the patient registration at the touch display of the When the patient is registered at the touch display, the scanner, the operator of the system has the possibility to same patient is automatically selected at the MR AWP select the next patient from the scheduler directly on the and the scan queue is loaded. scanner. Patient details such as age, name, program, body region, laterality, etc. can be checked. Patient orientation, weight and height can be checked, corrected or entered directly if needed. After checking, correcting and entering the values, the patient can be registered as the next patient to be scanned. Henderson, Christopher X Register Patient X Register Patient X Demographics 12 Procedure (s) Scheduled Today C 12 Procedure(s) Scheduled Today Last Name First Name Henderson Christopher To Patient Details Procedure Date & Tim Ho Patient Details Procedure Date & Time Gender Patient ID* Henderson, Christopher C-Spine 10:00 AM Henderson, Christopher C-Spine 10:00 AM Male abd-349.tnrid-35kdiu *03.04.1967 · M - 67819he0918 16.01.2023 *03.04.1967 . M . 67819he0918 16.01.202 Date of Birth* Chronic kidney failure Chronic kidney failure 03/04/1967 Age (years)" Hip 10:45 AN Brown, Charlie Hip Height (ft)* Height (in)" *03.04.1967 . M . 609egfh8353 16.01.2023 *03.04.1967 . M . 609egfh8353 16.01.2023 Was 515)" Smith, Peter Head 11:30 AM Smith, Peter Head 11:30 AM 242,51 *1983-05-19 - M - 375433sfa39h 16.01.2023 *1983-05-19 . M . 375433sfa39h 16.01.2023 Examination Details Grey, Meredith Head 12:15 AM Grey, Meredith Head 12:15 AM 1998-10-22 . F . 3754321sf399 16.01.2023 *1998-10-22 . F . 3754321sf399 16.01.2023 Program Selection* SIEMENS > head > Brain Assist > program Body Part (Laterality)" Silver, Elizabeth Sophie Thorax 02:30 PM 16.01.2023 Silver, Elizabeth Sophie Thorax 02:30 PM *1995-05-19 . F . 947463sfa322 *1995-05-19 . F . 947463sfa322 16:01 2023 Brain RF Transmit Mode Any Polarization Shepard, Clara Ankle 3:15 PM Shepard, Clara Ankle 03:15 PM *1974-03-18 . F . 947463hhdkg 16.01.2023 *1974-03-18 . F . 947463hhdkg 16.01.2023 Patient Orientation* Edit Head First Supine Mendoza, Jose Prostate 03:45 PM 16:45 Pm23 Prostate 03:45 PM 1971-09-14 . M . hfzfbakidosllp34 *1971-09-14 . M . hfzfbakidosllp34 16.01.2023 Medical Alerts Allergies Chronical Kidney Failure nove Karaci, Ozgur Head 04:15 PM Karaci, Ozgur Head 04:15 PM *1978-06-18 . M . jdfq93774hdudgL 16.01.2023 *1978-06-18 . M . jdfq93774hdudg! 16.01.2023 Krawczyk, Tamara Breast 05.00 PM Krawczyk, Tamara Breast 05:00 PM *1985-11-01 . F . dudoj85hdofnt3 16.01.2023 1985-11-01 - F . dudoj85hdofnt3 16.01.2023 Validate and confirm! Mandatory information Save Registration Patient Details Patient Details 20 syngo MR XA70A – What’s New 2. New coils 2.1. BioMatrix Head/Neck 20 tiltable coil with CoilShim Available for: MAGNETOM Avanto Fit Category: Purchasable option Pre-requisites: None Restrictions: None What is BioMatrix Head/Neck 20 tiltable coil Highlights and benefits: with CoilShim? • More comfortable positioning for patients undergoing The BioMatrix Head/Neck 20 tiltable coil with CoilShim head and neck examinations combines the known benefits of Tim 4G coil technology • Better image quality in diffusion imaging due to better- with those of the new and unique BioMatrix technology quality fat saturation when using CoilShim of Siemens Healthineers, resulting in unmatched image • quality, high patient comfort and easy handling. Localizer sequences automatically move to match the tilt of the coil for faster examination set-up. The integrated CoilShim elements minimize patient- • Three positions include: 0, 9, and 18 degrees of tilt induced local anatomy-specific B0 field inhomogeneity, thus ensuring excellent image quality. The unique DirectConnect technology allows users to connect the 20 coil elements of the BioMatrix Head/Neck 20 without cables. The coil has a patient-friendly open design and can be tilted in three different positions to provide maximum patient comfort. 21 syngo MR XA70A – What’s New 3. Improvements to sequences, protocols, and applications 3.1. Complex averaging Included with AdvanceNow Available for: MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, MAGNETOM Sola Fit, and MAGNETOM Viato.Mobile Category: Standard Pre-requisites: None Restrictions: None Diffusion-weighted imaging can be challenging due to number of averages – so that by preserving the entire the lower signal-to-noise ratio (SNR). To enhance SNR, range of signal obtained from the MRI system, it is often multiple images are acquired, which are subsequently possible to achieve substantially better SNR contrast averaged. In complex averaging, the noise remains zero through averaging. centered and scales inversely with the square root of the 3.2. Dual-polarity GRAPPA Included with AdvanceNow Available for: MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, MAGNETOM Sola Fit, and MAGNETOM Viato.Mobile Category: Standard Pre-requisites: None Restrictions: None Dual-polarity GRAPPA (DPG) is an advanced method It is recommended to use DPG with the new FLEET/ to determine robust GRAPPA weights for EPI imaging. Separate reference scan for optimal results. For more Employing DPG reduces ghosting artifacts in the final details, see: Hoge W.S. and Polimeni J.R.: Dual-Polarity reconstructed images due to its better high-order phase GRAPPA for Simultaneous Reconstruction and Ghost error resilience. DPG is enabled by a checkbox on the Correction of Echo Planar Imaging Data; Magn Reson Sequence -> Part 2 tab called “Ghost Reduction”. Med 76:32-44 (2016) SIEMENS > head > library > diffusion >> ep2d_diff_mddw_p2_b2000 SIEMENS . head > library > difusion . epad_dit_mddw_20_p? 3 4:39 min 4 Auto @ 2 @ 1.7x1.7x4.0 mm3 + 1.00 < Auto 23 2 @ 1.7-1.7-4.0mm 1.00 Protocol Parameters Routine Contrast Resolution| Geometry System Physio Diff Inline Sequence Protocol Paraneben Routine Contrast Resolution Geometry System Physio Inline Sequence Voice Commands Part 1 Part 2 Voice Communes Execution Assistant Acceleration Filter Image Management Introduction Acceleration mode GRAPPA Deep Resolve Cit Auto Load Auto Load Copy References Copy References Phase Partial Fourier 68 ference Scam FLEETIS .. Phase Correction External Tion Factor PE GRE/Separate ETYSeparate Ghost Reduction Des PE Fast GRE/Separate FLEET/Separane 22 syngo MR XA70A – What’s New 3.3. Inline filter Included with AdvanceNow Available for: MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, MAGNETOM Sola Fit, and MAGNETOM Viato.Mobile Category: Standard Pre-requisites: None Restrictions: None Additional functionality that allows users to enable or the inline filter in MRI can lead to improved image disable the inline image filter manually. This can be done quality, enhanced tissue characterization, increased under the image filter settings as shown below. The flexibility in postprocessing, and expanded capabilities inline filter can be controlled in the service user interface for quantitative analysis and research applications. and is typically active. In specific body regions, removing General 4:06 min Auto @ None 0.3x0.3x3.0 mm3 ¥ 1.00 Protocol Parameters Routine Contrast Resolution Geometry System Physio Inline Sequence Voice Comm Execution Image Filter Settings ? X Image Mana Auto Load ! Intensity Medium Copy Refere Preview Edge Enhancement 3 Debug Proto Smoothing Debug Licer Unfiltered Images Debug Exam Restrictions Inline Filter Close 23 syngo MR XA70A – What’s New 3.4. Lock TR and FA for BOLD imaging Included with AdvanceNow Available for: MAGNETOM Avanto Fit, MAGNETOM Skyra Fit, MAGNETOM Sola Fit, and MAGNETOM Viato.Mobile Category: Standard Pre-requisites: None Restrictions: None Locking the transverse relaxation (TR) and flip angle (FA) It also optimizes the TR and FA parameters and maximizes parameters in blood oxygen-level-dependent (BOLD) MR the signal-to-noise ratio (SNR), improving image quality imaging offers several advantages. Locking the TR and FA and sensitivity to changes in brain activity while reducing ensures that the Ernst Angle is matched to achieve the artifacts such as motion or susceptibility artifacts. best possible SNR. This ensures consistency across scans, This standardization also enables better comparison enhancing the reliability of longitudinal studies and between different studies, enhancing reproducibility facilitating comparisons between subjects or sessions. and generalizability of results. Routine Contrast Resolution Geometry System Physio BOLD Inline Sequence Common Dynamic TR 3000.0 ms Fat-Water Contrast Fat Saturation TE 50.00 ms MTC Flip Angle Optimization V Flip Angle 85 + deg Reconstruction Magnitude 24 syngo MR XA70A – What’s New Overview MAGNETOM Avanto MAGNETOM Skyra MAGNETOM MAGNETOM Fit BioMatrix Fit BioMatrix Sola Fit Viato.Mobile Deep Resolve for TSE, EPI and HASTE Deep Resolve Swift Brain Cardiac AutoMate 3D Whole Heart Pro BioMatrix Beat Sensor BioMatrix Coil Shim myExam Implant Suite myExam 3D Camera myExam Advanced Angio Assist myExam Autopilot Physiologging SVS Edit BLADE Diffusion HASTE Diffusion Open Recon Interactive Realtime Needle Guidance Select&GO Patient Registration Standard feature Optional feature Available as part of a previous software version 25 Siemens Healthineers pioneers breakthroughs in The outcomes and statements provided by customers healthcare. For everyone. Everywhere. Sustainably. The of Siemens Healthineers are unique to each customer’s company is a global provider of healthcare equipment, setting. Since there is no “typical” hospital and many solutions and services, with activities in more than 180 variables exist (e.g., hospital size, case mix, and level of countries and direct representation in more than 70. The service/technology adoption), there can be no guarantee group comprises Siemens Healthineers AG, listed as SHL that others will achieve the same results. in Frankfurt, Germany, and its subsidiaries. As a leading medical technology company, Siemens Healthineers is On account of certain regional limitations of sales rights committed to improving access to healthcare for and service availability, we cannot guarantee that all underserved communities worldwide and is striving to products included in this brochure are available through overcome the most threatening diseases. The company the Siemens Healthineers sales organization worldwide. is principally active in the areas of imaging, diagnostics, Availability and packaging may vary by country and is cancer care and minimally invasive therapies, augmented subject to change without prior notice. Some/All of the by digital technology and artificial intelligence. In fiscal features and products described herein may not be 2024, which ended on September 30, 2024, Siemens available in the United States. Healthineers had approximately 73,000 employees worldwide and generated revenue of around €22.4 billion. The information in this document contains general technical descriptions of specifications and options as Further information is available at well as standard and optional features, which do not www.siemens-healthineers.com. always have to be present in individual cases. Siemens Healthineers reserves the right to modify the design, packaging, specifications, and options described herein without prior notice. For the most current information, please contact your local sales representative from Siemens Healthineers. Note: Any technical data contained in this document may vary within defined tolerances. Original images always lose a certain amount of detail when reproduced. Siemens Healthineers Headquarters USA Siemens Healthineers AG Siemens Medical Solutions USA, Inc. Siemensstr. 3 Healthcare 91301 Forchheim, Germany 40 Liberty Boulevard siemens-healthineers.com Malvern, PA 19355-9998, USA siemens-healthineers.us Published by Siemens Healthineers AG · MR-25-NAM-7319 · QR700026501 · 07.2025 · ©Siemens Healthineers AG, 2025

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