Specimen Validity Testing

Meet Scott, a patient in a drug treatment program. He's recently used oxycodone and is trying to figure out how to beat his upcoming drug test. He's heard of ways to dilute, adulterate and substitute his urine to pass his screening and is willing to try anything. As a lab director, Catherine understands that Scott might be desperate and could attempt to alter his urine sample with in vivo methods such as body flushes, fluids and other products. Or he might use in vitro methods such as sample tampering or. Additives, Catherine. Knows the importance of having measures in place to detect sample. Adulteration. She relies on the full portfolio of specimen validity testing products from Siemens Health and EARS. The first sample. Attribute she. Can test for is creatinine, which appears in urine in relatively consistent quantities with normal. Water consumption If Scott consumes a large amount of water to dilute his urine, the creatinine validity test from Siemens Health in EARS will alert Catherine. To reduce. Creatinine levels. A second indicator she can also test for is specific. Gravity. This is an indicator of the density of urine, which should be higher than water. A reading outside the normal range of 1.003 to 1.030 may be the result of specimen dilution or added dissolved solids such as sodium chloride or sodium bicarbonate. This test is often used along with creatinine to evaluate specimen validity. Another. Indicator is nitrite, which is normally found in urine at low concentrations. Nitrites are a common component of additive salt on the Internet to hide the presence of drugs or result in the decomposition of a substance in a urine sample. If Scott adds A substance to master drug in his sample, the nitrite specimen validity test from Siemens Health and EARS will alert Catherine of abnormally high concentrations. Of. Nitrite Using tests from Siemens Health and EARS, Catherine can also identify adulterated or invalid specimens by their pH levels. An extremely high or low pH can be an indication of sample tampering or adulteration with added acidic. Or. Alkaline added products Finally, Catherine can test for oxidants such as pyridinium, chloro, clomate, bleach, and other substances found in various additives available on the Internet, none of which are found in normal human urine. If Scott tries to beat his test, Catherine can rest assured. That he will not succeed. Siemens Healthoneers have safeguards in place to flag these types of attempts. The full portfolio of specimen validity test from Siemens Healthoneers provides confidence in identifying patient samples that may be diluted, adulterated or substituted. Remember, detecting substance use is an important aspect of the care continuum because treatment starts with a test.

1.003 12 In vivo In vitro 1 Creatinine 2 Specific Gravity 3 Nitrite 4 pH 5 Oxidants Nitrite pH creatinine 10mg specific gravity non-adulterated sample dilution of sample adulteration by added solids in sample 20mg nitrite pH Levels oxidants BLEACH Oxidants SIEMENS Healthineers Specimen Validity Testing from Siemens Healthineers: Your Partner in Detecting Adulteration All trademarks are the property of their respective owners. Product availability may vary from country to country and is subject to local regulatory requirements. Please contact your local representative for availability.