MR Perfusion Maps - Numaris X

MR Perfusion Maps – Numaris X MR Perfusion Maps – Numaris X MR Neurology workflow is used to display and evaluate Perfusion Weighted images and to calculate Perfusion Maps, such as PBP, TTP, relCBV, relCBF, and relMTT. These perfusion maps show different perfusion characteristics of underlying tissue. Note: MR Perfusion datasets must either use distortion-correction or non-distortion correction image data, you cannot combine both. 1. From the Patient Browser, load the Perfusion data set into the MR Neurology workflow. a. Right-click on the examination and select Open with > MR Neurology. XASUA Open Ctrl+O XA30A @ Open with - Favorites View as Read-Only with Suggested Batch Open MK DIEVIS Assign Workflow MR Cardiac Analysis Cancel Workflow MR Neuro 3D MR Neurology Search Patient with DICOM Q/R MR Oncology Add to Demo List MR Prostate Remove from Demo List MR Spectro * Set Mark state . More 2. Case Navigator > Left-click on the Perfusion Maps icon. a. The New layout MR Neurology Reading > Perfusion Maps Viewing Layout opens. MR Neurology Ce + MR Neurology Reading Learn Perfusion Mismatch Click Segment Maps Eval. Mean Neurolo ... Curve Morpho ... Settings Viewing OH Pre-Contrast Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Global AIF Workflow – manually defines the Arterial Input Function (AIF) curve. It determines the position of the 5x5 ROI in the images and chooses the individual voxels considered for multi-selection, an average signal-time curve is displayed. 1. In the lower right segment, select the Global AIF tab to create Perfusion Maps. 2. Scroll through the Perfusion Weighted Images. a. Select an image when the contrast agent arrives in the region of interest. b. Drag the ROI to the area of interest and position the ROI over arteries (smaller arteries not explicitly recognizable as vessels) in the upper left image. c. In the Lower Middle Segment, the signal-time curves for reaching voxel update accordingly. AFL AFI Aera_Head CHUIMI Aera_Head CHUIMI Spain_MAC_1aaaa1990 Ref.: DemoCongress Spain_MAC_1aaaa1990 Ref.: DemoCongress 5/1/2014, F, 4Y Aera *5/1/2014, F, 4Y Aera 5/2/2018 MR E11 HFS 5/2/2018 MR E11 HFS ep2d_perf_basic_p2 +LER SWI_Images +LPA latest/Phase_01 latest # VE11C #VE11C STUDY ID 1aaaa1 990 STUDY ID 1 aaaa1990 16 IMA 13 15 IMA ~24 RFP RFP 1 cm SL MPR SPC SL SPC 0.8 E IPU SP H3.9 TA 02:48 FOV 220*220 TE 20.0 TP O BW 1700.0 128*128 BW 80.0 SP H3.9 p2 MIND Tra>Cor(25)>Sag(7) MPR THICK : ... WIND/NORM 173*288s A1/FS Zoom 3.82 A2 Tra>Cor(25)>Sag(7) HE3,4;NE1,2 N 2272 894 HE3,4;NE1,2 W 517 *epfid2d1_128 / 90 *qswi3d1r / 15 C 269 GADOLINIO 1.00ml No. of Timepoints: 50 Arterial Input Function (AIF) Perfusion Maps Global AIF Local AIF VTTP M PBP relCBF M reIMTT M relCBV relCBVCorrected O 4095 ASIST Perfusion Delay Correction Select All Clear All Start Close Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Page 2 of 7 3. In the Lower Middle Segment, select curves of voxels that should be considered for calculating the perfusion maps. a. Select One Arterial Input Function (AIF) time-point (or) Depress Ctrl/Left mouse > select more than one AIF time-point. i. Note: curves with the flattest baseline and deepest curve are most suitable. ii. Note: The number of AIF time points is up to the Radiologist's discretion (i.e., be consistent in the number of AIF time points selected). b. Lower Left Segment: AIF selections are displayed as a red curve. 4. To calculate the Perfusion Maps, drag a line to: a. Beginning of the Baseline. b. End of Baseline. c. End of First Pass. AFL AFL Aera_Head CHUIMI Aera_Head CHUIMI Spain_MAC_1 aaaa1990 Ref.: DemoCongress Spain_MAC_1aaaa1990 Ref.: DemoCongress 5/1/2014, F, 4Y Aera *5/1/2014, F, 4Y Aera 5/2/2018 MR E11 5/2/2018 MR E11 HFS HFS ep2d_perf_basic_p2 +LPR SWI_Images +LPA latest/Phase_01 latest # VE11C # VE11C STUDY ID 1aaaa1990 16 IMA 13 O STUDY ID 1aaaa1 990 15 IMA ~24 RFP RFP MPR 1cm SPC SL R SPC TA 02:48 FOV 220*220 TE 20.0 TP 0 128*128 BW 80.0 SP H3.9 p2 MIND Tra>Cor(25)>Sag(7) MPR THICK : ... WI/ND/NORM 173*288s A1/FS Zoom 3.82 A2 Tra>Cor(25)>Sag(7) HE3,4;NE1,2 W 2272 *epfid2d1_128 / 90 C 894 HE3,4;NE1,2 W 517 *qswi3d1r / 15 C 269 GADOLINIO 1.00ml No . of Timepoints : 5 Arterial Input Function (AIF) Perfusion Maps Arterial Input Function (AIF) Global AIF ocal AIF ¥ TTP PBP M relCBF M reIMTT ¥ relCBV relCBVCorrected O 4095 ASIST Perfusion ¥ Delay Correction Select All Clear All Start Close Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Page 3 of 7 5. Check the boxes to generate maps: TTP, relCBF, relCBV, PBP, relMTT. a. Delay Correction (optional). i. Block-circulate-deconvolution method for Global AIF (increases calculation time). ii. Different arrival times of contrast medium are considered. iii. Note: only perform this step if the reference ROI is too far away from the ROI to be measured. 6. Select Start, the Perfusion Tools area closes during map calculation. a. Progress Bar in Case Navigator shows the status of the calculation process. b. Maps are created. c. Findings created: creates a snapshot where the AIF was specified. Perfusion Maps Aera_Head CHUIMI Aera_Head Spain_MAC_1a83a1990 "5/1/2014, F. 4Y Ref: DerroCongress Spain_MAC_138381990 Aera *5/1/2014, F. 4Y 5/2/2018 MR XA70 5/2/2018 RELCBY_GLOBAL_ap2d_pet OLPH TTP_ap2d_pert_basic_p2_D Global AIF latest latest Local AIF €VE110 # VE11C STUDY ID 1sa8a1 990 STUDYID 188881900 1019 IVA1 FRM 15/33 1021 IKA 1 FRM 15/33 M TTP PBP RFP RFP 2D 20 ¥ relCB ¥ reIMTT 40 SL BPC BPC TP Q SP H12.7 ¥ relCBV relCBVCorrected FoV 220-220 TA02 48 BWV 1700.0 BW 1700.0 p2 MAGNIPERFACE 120'120 Tra>Cor(25)>>Bag(7) p2 MAGNUPERF/TTP Zoom 3.02 HG3,4 NG1,2 WY 1238 HE 3,4,NG1,2 eptd201_128 /90 "epid2c1_128 790 0 4095 ASIST Perfusion Aera Head CHUIMI Aera Head Spain_MC_1asa=1990 Ref: DerzoCengress Spain_IMAC_1aaaa1990 . "5M/2014, F. 4Y kera *5/1/2014, F. 4Y r DemeCongress 5/2/2018 MR XA70 HFS 5/2/2018 Delay Correction RELMITT_GLOBAL_6028_port_b OLPH PBP_ep2d_seit_basic_p2_DC Latest atest VE110 # VE11C STUDY ID 183831 990 STUDYD 188߆ 1022 IMA1 FRM 15/33 1023 IKA 1 FRM 18/33 RFP 20 BL R SPC R TP O TP O TA02.48 SP H12.7 SP H17.1 FoV 220 220 TA02:48 BWV 1700.0 FoV 220-220 BWV 1700.0 Start Close P2 MAONPERFATT 120 1 20 Tra Cor(26).Bag(7) D2 MAGNUPERFISCK 120 120 Tra>Con(25).Sag(7) MES Zoom 3.82 Zoom 3.82 HE3,4 NE1,2 W 2132 HE3,4, NE1,2 W 1688 "sp11201_128 /90 C 1020 "epto2c1_128 /90 950 7. Save Results. Save and Send: Results are stored on the system and sent to your archive. II Save and Pause: Results are stored on the system. Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Page 4 of 7 Local AIF Method Workflow: automated map calculation using standard input parameters. 1. Check boxes to create maps: TTP, relCBF, relCBV, relMTT. a. relCBV Corrected: includes a T1 correction (considering special effects of contrast media). 2. Select Start, the Perfusion Tools area closes during map calculation. b. Progress Bar in Case Navigator shows the status of the calculation process. c. Maps are created. AFL AFL Aera_Head CHUIMI Aera_Head CHUIM Spain_MAC_1aa Ref.: DemoCongress Spain_MAC_1aaaa1990 Ref.: DemoCongress *5/1/2014, F, 4Y Aera *5/1/2014, F, 4Y 5/2/2018 MR E11 RE11 HFS 5/2/2018 HFS ep2d_perf_basic_p2 SWI_Images latest/Phase_01 latest #VE11C # VE11C STUDY ID 1 aaaa 1990 STUDY ID 1aaaa1990 16 IMA 13 15 IMA ~24 RFP RFP 1 cm LU 2D MPR SL SL SPC R SPC 0.8 TP 0 SP H3.9 TA 02:48 FoV 220*220 TE 20.0 TP 0 BW 1700.0 128*128 BW 80.0 SP H3.9 p2 MIND Cor(25)>Sag(7) MPR THICK : ... WIND/NORM 173*288s A1/FS Zoom 3.82 A2 Tra>Cor(25)>Sag(7) HE3,4;NE1,2 W 2272 W 517 *epfid2d1_128 / 90 C 894 HE3.4:NE1.2 *qswi3d1r/ 15 C 269 GADOLINIO 1.00ml No. of Timepoints: 50 Arterial Input Function (AIF) Perfusion Maps Global All Local AIR TTP PBP ¥ relCBF ¥ reIMTT VreICBV relCBVCorrected 0 4095 ASIST Perfusion Delay Correction Select All Clear All Start Close Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Page 5 of 7 AFL AFL Aera_Head CHUIMI Aera_Head CHUIMI Spain_MAC_1 aaaa1990 Ref.: DemoCongress Spain_MAC_1aaaa1990 *5/1/2014, F, 4Y Aera *5/1/2014, F, 4Y Ref.: DemoCongress 5/2/2018 MR XA70 HFS 5/2/2018 1R XA70 RELCBF_LOCAL_ep2d_perf +LPH TTP_ep2d_perf_basic_p2 latest latest # VE11C #VE11C STUDY ID 1aaaa1990 STUDY ID 1aaaa1990 1036 IMA 1 FRM 15/33 1037 IMA 1 FRM 15/33 RFP RFP 2D 2D SL SL SPC SPC 4.0 TP O TP 0 SP H12.7 SP H12.7 TA 02:48 FoV 220*220 TA 02:48 FoV 220*220 BW 1700.0 128*128 BW 1700.0 128*128 p2 MAGN/PERF/RCBF Tra>Cor(25)>Sag(7) p2 MAGN/PERF/TTP Tra>Cor(25)>Sag(7) A1/FS Zoom 3.82 Zoom 3.82 HE3,4;NE1,2 W A1/FS W 75 *epfid2d1_128 / 90 C HE3,4;NE1,2 *epfid2d1_128 / 90 C 38 Local AIF Contrast agent 1.00ml Contrast agent 1.00ml AFL AFL Aera_Head CHUIMI Aera_Head CHUIMI Spain_MAC_1aaaa1990 Ref.: DemoCongress Spain_MAC_1aaaa1990 Ref.: DemoCongress *5/1/2014, F, 4Y Aera *5/1/2014, F, 4Y Aera 5/2/2018 MR XA70 5/2/2018 MR XA70 HFS HFS RELMTT_LOCAL_ep2d_perf_b +LPH RELCCBV_LOCAL_ep2d_perf_basicap +LPH latest latest # VE11C # VE11C STUDY ID 1aaaa1990 STUDY ID 1 aaaa1990 1038 IMA 1 FRM 15/33 1054 IMA 1 FRM 15/33 RFP RFP SL SL SPC R TP O TP O TA 02:48 SP H12.7 SP H12.7 FoV 220*220 TA 02:48 FOV 220*220 BW 1700.0 128*128 BW 1700.0 128*128 p2 MAGN/PERF/MTT Tra>Cor(25)>Sag(7) p2 MAGN/PERF/RCBV Tra>Cor(25)>Sag(7) A1/FS Zoom 3.82 Zoom 3.82 HE3,4;NE1,2 W A1/FS C 263 HE3,4;NE1,2 W 785 *epfid2d1_128 / 90 *epfid2d1_128 / 90 C 392 ontrast agent 4:00ml Local AIF : relcByCorr Contrast agent 1:00ml 3. Save Results. Save and Send: Results are stored on the system and sent to your archive. II Save and Pause: Results are stored on the system. Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Page 6 of 7 Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collec- tively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not neces- sarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Copyright © Siemens Healthineers AG 2025 Siemens Healthineers Headquarters Local Contact Information Legal Manufacturer Siemens Healthineers AG Siemens Medical Solutions USA, Inc. Imaging & Therapy Systems Siemensstraße 3 40 Liberty Blvd. Magnetic Resonance 91301 Forcheim, Germany Malvern, PA 19355-9998 USA Henkestr. 127 Phone: +49 9191 18-0 Telephone: +1-888-826-9702 DE-91052 Erlangen siemens-healthineers.com Customer Care Telephone: Germany +1-800-888-7436 Telephone: +49 9191 18-0 Unrestricted | Published by Siemens Healthineers AG, 2025 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 02/10/2025 | QR700018463 Healthineers Page 7 of 7