AI-Rad Companion Brain MR – Neuroimaging Workflow

Hello everyone, my name is Amit and I'm the global product manager for air at companion Branemark and today we have with us. Met very happy to have you met. Thank you for having me. Why don't you tell us something about yourself and what your experience has been so far with the error companion bring EMR? Thank you, I'm a neurologist at the Department of Neuroradiology in the university Clinic Manheim, and we used the ERP company in Mr Brain software in our dementia protocols to evaluate patients. So let's take a look at the current imaging workflow at our institution. After a patient receives an MRI, an expert takes a look at the images in all segments sequences. And uses their experience to provide few visual empirical scores that are scored on a granular scale from zero to three, meaning minor or severe changes. The problem, however, with these empirical scores that they show a huge variability and not only between readers but also between multiple time points. So an additional problem is, and additional pitfall if the technical assistant. We're doing the reconstruction, maybe incorrectly angulatus the image. On the uer side of this. T1V TMP rage image. We can see a correct angulation and see that the hydrochemical volume of the 79 year old patient is actually normal for his age. Receiving an MTA score of two. However, if the angulation is incorrect, angulated, according to the brainstem, we receive a pathological score of MTT score 3. So what, what the future holds and what we are expecting from the future? How should we modify our imaging workflow? The image on the right side? Shows the results of the AI Red companion Mr Brain software tool that we use at our institution currently. O, let's take a look at this 79 year old male patient again. He had a minor cognitive impairment and accordingly he received the Mini mental score of 25 out of three and he additionally had cardiovascular risk factors like arterial hypertonia or Type 2 diabetes and hypercholesterolemia. If you take a look at the left side image that's at 2 flare image, we can see that he has white matter hyperintensities in his pawns in his brain stem that also called. Strategically lesions and if you take a look at this whole brain image, now you can see that he has an extensive confluent bites material. Lesions are eventually and also in the deep white matter, so accordingly, this patient received the physical score of three, which suggests microvascular disease and vascular dementia. However, if we evaluate the whole brain using brain morphometry and Mr brain tool, we can see that this patient also has severe temporal atrophy on the left side. While we can approve and confirm. That the initial slight angulation with the Metascore 2 of the hyper combos was correct was provided on the right image. O we not only have other patients, but also younger patients with suspect in neuroinflammatory diseases by this 19 year old female patient she presented to the ER department with the vision, loss and loss of color and hyperesthesia in her right eye. If you take a look at her two space image on the left side, we can see multiple lation Supra and infratentorial as the wide area show and two further. To pretend to relations and has contrast agent suggesting activity and additionally also the optic nerve on the right side. Responsible for visual symptoms and according to the McDonald criteria, this patient had chronic central nervous system, inflammatory disease and qualified for the diagnosis. Multiple sclerosis. So taking together from an AI enhanced new imaging workflow, we want precision medicine and trustable high quality results that we can use. For an improved classification and diagnosis of the patients and also additionally for predictive modeling to provide the best possible care and theoretic approaches.

4. 5. 6. 3. Amit Shah Global Product Manager Al-Rad Companion Brain MR, Siemens Healthineers Matt Maros MD MSc Department of Neuroradiology, Medical Faculty Mannheim, Heidelberg University UMM neuro radiologie der Universität Heidelberg MANNHEIM Universitätsklinikum Mannheim Ai-based neuroimaging: a companion for precision medicine Máté (Matt) Maros MD, MSc1,2 RSNA 2021 REDEFINING RADIOLOGY November 28 to December 2 107th Scientific Assembly and Annual Meeting SIEMENS Healthineers Current Neuroimaging Workflow MRI ? #% 1. GCA-scale 2. MTA-scale 3. Koedam score 4. Fazekas scale 5. Strategic infarcts · Requires expert-knowledge ("engrams of normal") · Few semi-quantitative scores · High intra- and interrater variability Challenges and pitfalls 79y, m Slice orientation and angulation MTA Score = 2 Ai-enhanced Neuroimaging Workflow Ai post-processing · Improved reader confidence & reliability · Automated reporting · Improved longitudinal comparability Let's revisit the previous case FLAIR MCI - mild cognitive impairment MMSE - Mini-Mental State Exam: 25 / 30 Cardiovascular risk factors Arterial hypertension (aHT) Type 2 diabetes (T2D) Hypercholesterolemia (HC Confluent White Matter Lesions (WML) Images were created with Al Rad Companion Brain MR 1. MTA: 2. Koedam: 3. Fazekas: 4. Asymmetry: No Microvascular Disease Significant temporal asymmetry What about young patients? 19y, f T2 SPACE T1ce T1sub T1fs 1. WML: 2. Supratentorial: 3. Infratentorial: Optic nerve: DWI: Contrast E .: McDonald criteria > Multiple Sclerosis Precision medicine Classification Predictive modeling Please note that the learning material is for training purposes only. For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively "Operator Manual") issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Please note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively "Functionality") may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Siemens Healthcare GmbH 2022 Siemens Healthineers are neither the provider nor legal manufacturer of this video. Any claims and statements made in this video and any content shown in the video are under the sole responsibility of the provider. Additionally, the services may not be available in all countries and the content may not be commercially available in all countries. Please contact the provider for more information.